Packard A B, O'Brien G M, Treves S
Int J Rad Appl Instrum B. 1986;13(5):519-22. doi: 10.1016/0883-2897(86)90131-5.
A 191Os----191mIr generator has been developed that has higher 191mIr yield and lower 191Os breakthrough than previous designs. These improvements have been realized through the use of the osmium chelate complex trans-dioxobismalonatoosmate(VI) as the parent species on the generator. The new generator provides an initial 191mIr yield of 40%/mL and 191Os breakthrough of 2-3 X 10(-3)% when eluted with a solution of 0.05 M malonic acid/0.10 M sodium chloride at pH 4. Other advantages of the new design include faster clearance of the 191Os breakthrough products and simpler assembly.
已研发出一种191Os-191mIr发生器，其191mIr产率高于以往设计，且191Os穿透率低于以往设计。通过使用螯合锇配合物反式-二氧代双丙二酸锇(VI)作为发生器上的母体物质，实现了这些改进。当用pH值为4的0.05 M丙二酸/0.10 M氯化钠溶液洗脱时，新发生器的初始191mIr产率为40%/mL，191Os穿透率为2-3×10(-3)%。新设计的其他优点包括191Os穿透产物的清除更快以及组装更简单。
