Treves S, Kulprathipanja S, Hnatowich D J
Circulation. 1976 Aug;54(2):275-9. doi: 10.1161/01.cir.54.2.275.
Iridium-191m is a potential tracer for angiocardiography and may be of particular value in the evaluation of heart disease in children. It possesses a short half-life (4.9 sec), suitable photon energy (129 keV) and may be obtained as a generator product by decay of its long lived (15.3 day) parent 191 Os. An 191Os leads to 191mIr generator capable of providing 15 mCi of 191mIr in 1.5 ml of eluant is described. The separation of 191mIr from 191Os is achieved by absorbing 191OsC16-2 on an anion exchange resin. The generator employs an additional resin column which is replaced to prevent 191Os breakthrough to become excessive. By this procedure, the breakthrough may be kept below 0.001% over a period of at least one month and after multiple elutions.
铱 - 191m是一种潜在的心血管造影示踪剂，在评估儿童心脏病方面可能具有特殊价值。它具有短半衰期（4.9秒）、合适的光子能量（129 keV），并且可以通过其长寿命（15.3天）母体191Os的衰变作为发生器产物获得。描述了一种能够在1.5毫升洗脱液中提供15毫居里191mIr的191Os - 191mIr发生器。通过在阴离子交换树脂上吸附191OsC16 - 2实现191mIr与191Os的分离。该发生器采用了一个额外的树脂柱，该树脂柱会被更换以防止191Os的穿透变得过度。通过这个程序，在至少一个月的时间内以及多次洗脱后，穿透率可以保持在0.001%以下。
