相位角与 COPD 患者肌少症和肌肉功能的相关性：一项病例对照研究。
Association of phase angle with sarcopenia and muscle function in patients with COPD: a case-control study.
机构信息
Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, Tehran, Iran.
Department of Pulmonary and Critical Care, School of Medicine, Shariati Hospital, Tehran, Iran.
出版信息
BMC Pulm Med. 2024 Jan 6;24(1):18. doi: 10.1186/s12890-023-02814-9.
BACKGROUND AND AIMS
The predictive value of phase angle for sarcopenia diagnosis has been discussed for years. The present investigation was conducted to determine the association between phase angle and sarcopenia in patients with COPD.
METHODS
In this case-control study, 222 smoker men were divided into healthy and COPD groups. COPD was diagnosed by a pulmonologist through spirometry. Anthropometric indices, phase angle, muscle function, sarcopenia, and dietary intake were assessed.
RESULTS
A significant inverse association was observed between phase angle and sarcopenia after adjustment for age and energy intake (OR: 0.31, 95% CI 0.18-0.52) and after adjustment for BMI (OR: 0.31, 95% CI 0.18-0.52). A significant decrease was detected in anthropometric indices and indicators of sarcopenia and muscle function in COPD cases compared to the healthy controls.
CONCLUSIONS
Although further studies are suggested, phase angle might be considered an indicator of sarcopenia and muscle function in COPD patients.
背景与目的
相位角在肌少症诊断中的预测价值已讨论多年。本研究旨在确定相位角与 COPD 患者肌少症之间的关系。
方法
在这项病例对照研究中，222 名吸烟男性被分为健康组和 COPD 组。COPD 通过肺功能检查由肺病专家诊断。评估了人体测量指标、相位角、肌肉功能、肌少症和饮食摄入。
结果
在校正年龄和能量摄入（OR：0.31，95%CI 0.18-0.52）以及 BMI 校正后（OR：0.31，95%CI 0.18-0.52），相位角与肌少症呈显著负相关。与健康对照组相比，COPD 病例的人体测量指标和肌少症及肌肉功能指标显著下降。
结论
尽管还需要进一步的研究，但相位角可能被认为是 COPD 患者肌少症和肌肉功能的指标。
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