Hung Shih-Han, Xirasagar Sudha, Dang Luong Huu, Chen Yen-Chun, Cheng Yen-Fu, Lin Herng-Ching, Chen Chin-Shyan
Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, Taiwan.
Department of Otolaryngology, Wan Fang Hospital, Taipei, Taiwan.
Front Neurol. 2023 Dec 12;14:1322199. doi: 10.3389/fneur.2023.1322199. eCollection 2023.
This study aimed to examines the long-term trend of incidence of peripheral vestibular disorders between 2010 and 2018 in Taiwan.
Study-eligible patients were identified from Taiwan's Longitudinal Health Insurance Database 2005 maintained by the Ministry of Health and Welfare in Taiwan. We retrieved 230,566 patients with a first-time diagnosis of peripheral vestibular disorders between 2010 and 2018. We calculated annual incidence rates of peripheral vestibular disorders per 100,000 population. We used the annual percent change (APC) to test the trend of peripheral vestibular disorders over time.
The mean annual incidence rate of peripheral vestibular disorders during the study period was 1489.6 per 100,000 population. Incidence showed a statistically significant steady decrease from 2010 to 2018 with a mean APC of -6.15% (95% CI = -6.97% ~ -5.32%). The decline was led by Meniere's disease (APC = -9.83, 95% CI = -10.66% ~ -8.99%), followed by benign paroxysmal positional vertigo (APC = -3.69, 95% CI = -4.53% ~ -3.03%), vestibular neuritis (APC = -7.85, 95% CI = -8.96 ~ -6.73), and other peripheral vestibular dizziness (APC = -5.56, 95% CI = -6.69% ~ -4.43%).
The incidence of peripheral vestibular disorders, overall, and the four major subgroups, benign paroxysmal positional vertigo, Meniere's disease, vestibular neuritis, and other peripheral vestibular dizziness, all decreased substantially, year by year within the 2010-2018 period.
本研究旨在探讨2010年至2018年台湾地区周围性前庭疾病发病率的长期趋势。
符合研究条件的患者来自台湾地区卫生福利部维护的2005年台湾纵向健康保险数据库。我们检索了2010年至2018年间首次诊断为周围性前庭疾病的230566名患者。我们计算了每10万人口中周围性前庭疾病的年发病率。我们使用年变化百分比（APC）来检验周围性前庭疾病随时间的变化趋势。
研究期间周围性前庭疾病的平均年发病率为每10万人口1489.6例。发病率从2010年到2018年呈统计学显著的稳步下降，平均APC为-6.15%（95%CI = -6.97% ~ -5.32%）。下降主要由梅尼埃病（APC = -9.83，95%CI = -10.66% ~ -8.99%）导致，其次是良性阵发性位置性眩晕（APC = -3.69，95%CI = -4.53% ~ -3.03%）、前庭神经炎（APC = -7.85，95%CI = -8.96 ~ -6.73）和其他周围性前庭性头晕（APC = -5.56，95%CI = -6.69% ~ -4.43%）。
在2010 - 2018年期间，周围性前庭疾病总体发病率以及四个主要亚组，即良性阵发性位置性眩晕、梅尼埃病、前庭神经炎和其他周围性前庭性头晕的发病率均逐年大幅下降。
