外周前庭疾病与糖尿病的关联：一项基于人群的研究。
Association of Peripheral Vestibular Disorder with Diabetes: A Population-Based Study.
作者信息
Yang Tzong-Hann, Chen Chao-Hung, Cheng Yen-Fu, Lin Herng-Ching, Chen Chin-Shyan
机构信息
Department of Otorhinolaryngology, Taipei City Hospital, Taipei 100, Taiwan.
Department of Speech, Language and Audiology, National Taipei University of Nursing and Health, Taipei 112, Taiwan.
出版信息
J Pers Med. 2024 Jul 19;14(7):768. doi: 10.3390/jpm14070768.
BACKGROUND
This study aimed to investigate the association of peripheral vestibular disorders with type 1 and type 2 diabetes using a population-based dataset.
METHODS
The data for this study were obtained from Taiwan's Longitudinal Health Insurance Database 2010. The sample consisted of 150,916 patients who were newly diagnosed with peripheral vestibular disorders as cases and 452,748 propensity-score-matching controls without peripheral vestibular disorders. We utilized multivariate logistic regression models to quantitatively evaluate the association between peripheral vestibular disorders and diabetes while considering factors such as sex, age, geographic location, monthly income, urbanization level of the patient's residence, coronary heart disease, hypertension, and hyperlipidemia.
RESULTS
The chi-squared test indicates that diabetes was more common in the peripheral vestibular disorder group compared to controls (20.6% vs. 15.1%, < 0.001). Of all sampled patients, the adjusted odds ratio for diabetes was 1.597 (95% CI = 1.5701.623) for those with peripheral vestibular disorders when compared to controls, while patients with Ménière's disease, benign paroxysmal positional vertigo, unilateral vestibulopathy, and other peripheral vestibular disorders had respective adjusted odds ratios of diabetes at 1.566 (95% CI = 1.4981.638), 1.677 (95% CI = 1.6031.755), 1.592 (95% CI = 1.5041.685), and 1.588 (95% CI = l.555~1.621) in comparison to controls.
CONCLUSIONS
Our research has revealed an association between diabetes and an increased susceptibility to peripheral vestibular disorders.
背景
本研究旨在利用基于人群的数据集调查1型和2型糖尿病与周围性前庭疾病之间的关联。
方法
本研究的数据来自台湾2010年纵向健康保险数据库。样本包括150916例新诊断为周围性前庭疾病的患者作为病例组，以及452748例无周围性前庭疾病的倾向评分匹配对照组。我们使用多变量逻辑回归模型，在考虑性别、年龄、地理位置、月收入、患者居住的城市化水平、冠心病、高血压和高脂血症等因素的同时，定量评估周围性前庭疾病与糖尿病之间的关联。
结果
卡方检验表明，与对照组相比，周围性前庭疾病组中糖尿病更为常见（20.6%对15.1%，<0.001）。在所有抽样患者中，与对照组相比，患有周围性前庭疾病的患者患糖尿病的调整后优势比为1.597（95%CI=1.5701.623），而梅尼埃病、良性阵发性位置性眩晕、单侧前庭病和其他周围性前庭疾病患者患糖尿病的调整后优势比分别为1.566（95%CI=1.4981.638）、1.677（95%CI=1.6031.755）、1.592（95%CI=1.5041.685）和1.588（95%CI=l.555~1.621）。
结论
我们的研究揭示了糖尿病与周围性前庭疾病易感性增加之间的关联。
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