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迈向分子自组织和前细胞达尔文进化的实验分析。

Towards an experimental analysis of molecular self-organization and precellular Darwinian evolution.

作者信息

Küppers B

出版信息

Naturwissenschaften. 1979 May;66(5):228-43. doi: 10.1007/BF00571603.

DOI:10.1007/BF00571603
PMID:381944
Abstract

An experimental system is described, which opens up a novel pathway towards a molecular understanding of the origin of life. The systemic conditions for the evolution of biological macromolecules are investigated in detail.

摘要

描述了一种实验系统，它为从分子层面理解生命起源开辟了一条新途径。详细研究了生物大分子进化的系统条件。

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Towards an experimental analysis of molecular self-organization and precellular Darwinian evolution.迈向分子自组织和前细胞达尔文进化的实验分析。
Naturwissenschaften. 1979 May;66(5):228-43. doi: 10.1007/BF00571603.
2
Evolution in vitro: sequence and phenotype of a mutant RNA resistant to ethidium bromide.体外进化：抗溴化乙锭突变RNA的序列与表型
J Mol Biol. 1974 Nov 15;89(4):719-36. doi: 10.1016/0022-2836(74)90047-3.
3
Evolution of the RNA coliphages: the role of secondary structures during RNA replication.RNA 噬菌体的进化：RNA 复制过程中二级结构的作用。
Cold Spring Harb Symp Quant Biol. 1987;52:321-30. doi: 10.1101/sqb.1987.052.01.037.
4
Replication and evolution of short-chained RNA species replicated by Q beta replicase.由Qβ复制酶复制的短链RNA物种的复制与进化
Cold Spring Harb Symp Quant Biol. 1987;52:299-306. doi: 10.1101/sqb.1987.052.01.035.
5
Minimal requirements for template recognition by bacteriophage Qbeta replicase: approach to general RNA-dependent RNA synthesis.噬菌体Qβ复制酶识别模板的最低要求：通用RNA依赖RNA合成的方法
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Replicable RNA vectors: prospects for cell-free gene amplification, expression, and cloning.可复制RNA载体：无细胞基因扩增、表达及克隆的前景
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Synthesis of probes for RNA using Qbeta-replicase.使用Qβ复制酶合成RNA探针。
Biochem Biophys Res Commun. 1975 May 19;64(2):640-7. doi: 10.1016/0006-291x(75)90369-1.
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Template-directed and template-free RNA synthesis by Q beta replicase.Qβ复制酶介导的模板依赖性和非模板依赖性RNA合成
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RNA replication: function and structure of Qbeta-replicase.RNA复制：Qβ复制酶的功能与结构
Annu Rev Biochem. 1979;48:525-48. doi: 10.1146/annurev.bi.48.070179.002521.
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An approach to the experimental analysis of precellular evolution.
Q Rev Biophys. 1971 Aug;4(2):213-53. doi: 10.1017/s0033583500000639.

引用本文的文献

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Coding of Class I and II Aminoacyl-tRNA Synthetases.I 类和 II 类氨酰-tRNA 合成酶的编码。
Adv Exp Med Biol. 2017;966:103-148. doi: 10.1007/5584_2017_93.
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Compartmentalization of self-reproducing machineries: multiplication of microsystems with self-instructing polymerization of amino acids.自我复制机制的区室化：通过氨基酸的自我指导聚合实现微系统的增殖。
Orig Life. 1980 Dec;10(4):361-70. doi: 10.1007/BF00928309.
3
A neutral theory of biogenesis.生物发生的中性理论。

本文引用的文献

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Three complementation groups in bacteriophage R17.噬菌体R17中的三个互补群。
J Mol Biol. 1966 Nov 28;21(3):435-53. doi: 10.1016/0022-2836(66)90017-9.
2
Mutants of the bacteriophage f2. VI. Homology of temperature-sensitive and host-dependent mutants.
Virology. 1966 Mar;28(3):438-47. doi: 10.1016/0042-6822(66)90056-0.
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Enzymatic synthesis of deoxyribonucleic acid. XIII. Kinetics of primed and de novo synthesis of deoxynucleotide polymers.脱氧核糖核酸的酶促合成。十三。脱氧核苷酸聚合物引发合成与从头合成的动力学。
Orig Life. 1981 Dec;11(4):369-85. doi: 10.1007/BF00931491.
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Parasites at the origin of life.
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The improbability of prebiotic nucleic acid synthesis.益生元核酸合成的可能性极小。
Orig Life. 1984;14(1-4):565-70. doi: 10.1007/BF00933705.
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Polynucleotide evolution and branching processes.
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The synthesis of primitive 'living' forms: definitions, goals, strategies and evolution synthesizers.原始“生命”形式的合成：定义、目标、策略与进化合成器
Orig Life Evol Biosph. 1985;16(2):129-49. doi: 10.1007/BF01809467.
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SEROLOGICAL CROSS REACTIONS AMONG THE RNA-CONTAINING COLIPHAGES.含RNA的大肠杆菌噬菌体之间的血清学交叉反应。
Virology. 1965 May;26:85-8. doi: 10.1016/0042-6822(65)90028-0.
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STUDIES ON POLYNUCLEOTIDES. XL. SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE INFLUENCE OF TEMPERATURE ON TEMPLATE FUNCTION.多核苷酸研究。XL。作为核糖核酸聚合酶模板的合成脱氧核糖多核苷酸：温度对模板功能的影响。
J Biol Chem. 1965 Apr;240:1750-3.
6
RIBONUCLEASE DIGESTION OF R17 VIRAL RNA.R17病毒RNA的核糖核酸酶消化
J Mol Biol. 1965 Jan;11:84-9. doi: 10.1016/s0022-2836(65)80173-5.
7
ENZYMIC SYNTHESIS OF RNA WITH REOVIRUS RNA AS TEMPLATE. I. CHARACTERISTICS OF THE REACTION CATALYZED BY THE RNA POLYMERASE FROM ESCHERICHIA COLI.以呼肠孤病毒RNA为模板的RNA酶促合成。I. 大肠杆菌RNA聚合酶催化反应的特性
J Mol Biol. 1964 Jul;9:193-207. doi: 10.1016/s0022-2836(64)80100-5.
8
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION.脱氧核糖核酸的酶促合成，十六。作为模板的寡核苷酸及其复制机制。
Proc Natl Acad Sci U S A. 1964 Feb;51(2):315-23. doi: 10.1073/pnas.51.2.315.
9
AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES.一种由病毒RNA诱导并对其具有选择性的RNA“复制酶”：分离与特性
Proc Natl Acad Sci U S A. 1963 Nov;50(5):905-11. doi: 10.1073/pnas.50.5.905.
10
Homology test between the nucleic acid of an RNA virus and the DNA in the host cell.RNA病毒核酸与宿主细胞DNA之间的同源性检测。
Science. 1962 Dec 14;138(3546):1270-2. doi: 10.1126/science.138.3546.1270.