用于微重力研究的肾脏微生理系统硬件平台的开发。

Development of a Kidney Microphysiological System Hardware Platform for Microgravity Studies.

作者信息

Yeung Catherine, Jones-Isaac Kendan, Lindberg Kevin, Yang Jade, Bain Jacelyn, Ruiz Micaela, Koenig Greta, Koenig Paul, Countryman Stefanie, Himmelfarb Jonathan, Kelly Edward

机构信息

University of Washington.

BioServe Space Technologies.

出版信息

Res Sq. 2023 Dec 22:rs.3.rs-3750478. doi: 10.21203/rs.3.rs-3750478/v1.

DOI:10.21203/rs.3.rs-3750478/v1

PMID:38196654

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10775353/

Abstract

Study of the physiological effects of microgravity on humans is limited to non-invasive testing of astronauts. Microphysiological models of human organs recapitulate many functions and disease states. Here we describe the development of an advanced, semi-autonomous hardware platform to support kidney microphysiological model experiments in microgravity.

摘要

对微重力对人类生理影响的研究仅限于对宇航员进行非侵入性测试。人体器官的微生理模型概括了许多功能和疾病状态。在此，我们描述了一种先进的半自主硬件平台的开发，以支持在微重力环境下进行肾脏微生理模型实验。