Stornebrink Tobias, Walinga Alex, Dalmau-Pastor Miki, Bosman Anton W, Smit Theodoor H, Kerkhoffs Gino M M J
Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.
Amsterdam Movement Sciences, Amsterdam, the Netherlands.
Arthrosc Tech. 2023 Nov 27;12(12):e2343-e2352. doi: 10.1016/j.eats.2023.08.004. eCollection 2023 Dec.
Injectable implants constitute a newly developed treatment class in the battle against osteoarthritis. They consist of water-formulated supramolecular polymer, coming from a new class of resorbable biomedical materials, and are implanted in encapsulated joints in a liquid form, where they solidify to form a tough, elastic, and cushioning layer between the joint surfaces. To resort any effect, intra-articular delivery should be guaranteed, and the implant should be distributed throughout the entire joint space. Traditional implantation techniques do not seem to suffice for this new implant class, being either imprecise (traditional injection) or overly invasive (open procedures and traditional arthroscopic surgery). We describe a needle arthroscopic implantation technique to reap the benefits of both worlds, ensuring precise implant delivery while avoiding unnecessarily invasive procedures. This study depicts our needle arthroscopic technique for implantation of injectable implants in the ankle, first metatarsophalangeal joint, and first carpometacarpal joint.
可注射植入物是对抗骨关节炎新开发的一类治疗手段。它们由水基超分子聚合物组成，这种聚合物来自一类新型可吸收生物医学材料，并以液体形式植入密封关节，在关节内凝固形成一层坚韧、有弹性且具缓冲作用的层，位于关节表面之间。为实现任何效果，都应确保关节内给药，且植入物应分布于整个关节腔。传统植入技术似乎不足以应对这类新型植入物，要么不够精确（传统注射），要么侵入性过大（开放手术和传统关节镜手术）。我们描述了一种针式关节镜植入技术，以兼顾两者优点，确保精确植入给药，同时避免不必要的侵入性操作。本研究描述了我们在踝关节、第一跖趾关节和第一腕掌关节中植入可注射植入物的针式关节镜技术。
