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与味觉知觉功能障碍相关的因素。

Factors associated with impaired psychophysical gustatory function.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, South Korea.

Department of Applied Statistics, Chung-Ang University, Seoul, South Korea.

出版信息

Clin Otolaryngol. 2024 May;49(3):306-313. doi: 10.1111/coa.14143. Epub 2024 Jan 10.

Abstract

OBJECTIVE

To investigate the clinical characteristics associated with measured gustatory dysfunction in patients with chemosensory (smell and taste) discomfort.

STUDY DESIGN

Retrospective study.

DESIGN

Hospital-based cohort.

SETTING

The clinical characteristics associated with the measured diagnosis of gustatory dysfunction were statistically analysed.

PARTICIPANTS

Patients who underwent all the psychophysical olfactory and chemical gustatory function tests (YSK olfactory function test and chemical gustometry exam) and the subjective questionnaires between October 2021 and February 2023.

MAIN OUTCOME MEASURES

YSK olfactory function test and chemical gustometry results, subjective questionnaire score about chemosensory (smell and taste) functions. The Medical records of patients who visited the smell and taste centre in a tertiary.

RESULTS

A total of 219 patients were enrolled; 180 were diagnosed as having normal gustatory function, and 39 were diagnosed as having gustatory dysfunction. Subjective recognition of gustatory function was not associated with the measured gustatory function. Age, sex, measured olfactory function and the threshold and discrimination scores for the olfactory function test were significant factors in the multivariate analysis. When the patients were further divided according to age, the threshold test scores rather than other subsets in the olfactory function test were significantly associated with measured gustatory dysfunction in patients 60 and older.

CONCLUSION

In older adult male patients with olfactory dysfunction, gustatory function should be considered regardless of subjective gustatory dysfunction.

摘要

目的

研究与化学感觉(嗅觉和味觉)不适患者味觉功能障碍的测量相关的临床特征。

研究设计

回顾性研究。

设计

基于医院的队列。

地点

对与味觉功能障碍的测量诊断相关的临床特征进行统计学分析。

参与者

2021 年 10 月至 2023 年 2 月期间接受了所有心理物理学嗅觉和化学味觉功能测试(YSK 嗅觉功能测试和化学味觉测试)和主观问卷调查的患者。

主要观察指标

YSK 嗅觉功能测试和化学味觉测试结果、主观嗅觉和味觉功能问卷评分。三级嗅觉和味觉中心就诊患者的病历。

结果

共纳入 219 例患者;180 例诊断为味觉正常,39 例诊断为味觉障碍。味觉功能的主观识别与味觉功能的测量结果无关。年龄、性别、嗅觉功能的测量值以及嗅觉功能测试的阈值和辨别分数是多变量分析中的显著因素。当根据年龄进一步对患者进行分组时,在 60 岁及以上的患者中,只有嗅觉功能测试的阈值测试分数,而不是其他子集与味觉功能障碍的测量结果显著相关。

结论

在嗅觉功能障碍的老年男性患者中,无论主观味觉功能如何,都应考虑味觉功能。

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