Romeo G, Zuccarello B, Proietto F, Romeo C
J Pediatr Surg. 1987 Feb;22(2):120-4. doi: 10.1016/s0022-3468(87)80425-6.
Esophageal dysfunction has been reported after successful repair of esophageal atresia but its nature has not been clearly defined. We studied esophageal motility in 20 newborns with esophageal atresia by recording intraluminal pressure of both proximal and distal segments. The investigation was made by pressure monitoring of the upper pouch via the mouth and of the distal segment via the gastrostomy. In all cases we found motility disorders. Two patients (12.5%) showed incomplete relaxation of the upper esophageal sphincter. The resting pressure of the esophageal body in both segments was constantly positive in all cases. Lower esophageal sphincter (LES) function was normal in all but two patients (16.7%) in whom the LES pressure was reduced and one case (8.4%) with incomplete relaxation of the LES. These studies suggest that motility disorders are also present in esophageal atresia before surgery.
据报道，食管闭锁成功修复后会出现食管功能障碍，但其本质尚未明确界定。我们通过记录20例食管闭锁新生儿近端和远端节段的腔内压力，研究了其食管动力。通过经口对上段盲袋以及经胃造口对远端节段进行压力监测来开展此项研究。在所有病例中，我们均发现了动力障碍。2例患者（12.5%）表现为食管上括约肌不完全松弛。在所有病例中，两个节段食管体的静息压力始终为正。除2例患者（16.7%）的下食管括约肌（LES）压力降低以及1例患者（8.4%）的LES不完全松弛外，其余所有患者的LES功能均正常。这些研究表明，术前食管闭锁患者也存在动力障碍。
