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在临床实践指南(CPG)中,性别对生物医学方法重要吗?:对西班牙国家卫生系统中使用的方法学文件的系统评价

Does Sex Matter to the Biomedical Approach in Clinical Practice Guidelines (CPGs)?: A Systematic Review of Methodology Documents Used in the Spanish National Health System.

作者信息

González Ramos Ana M, Serrano-Gemes Gema

机构信息

Institute for Advanced Social Studies (IESA), The Spanish National Research Council (CSIC), 14004 Córdoba, Spain.

Department of Nursing and Physiotherapy, Ponferrada University Campus, University of León, 24401 Ponferrada, Spain.

出版信息

Healthcare (Basel). 2023 Dec 28;12(1):74. doi: 10.3390/healthcare12010074.

DOI:10.3390/healthcare12010074
PMID:38200979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10778633/
Abstract

Sex and gender are important variables in health, although their incorporation in medicine has been very slow. If research is sensitive and yields fruitful sex and gender evidence, these results should be included in the guidelines for clinical practices. However, literature claims that clinical practice guidelines devote very little space to these categories. The present systematic review addresses the relevance of sex and gender dimensions through methodology documents for the development of clinical practice guidelines based on three sources: the AGREE Reporting Checklist, the GRADE Handbook, and the Spanish GuíaSalud NHS Clinical Guideline Program. Findings suggest that neglecting sex and gender issues in the biomedical approach may lead to continuing to ignore relevant evidence on biological and social dimensions that do indeed influence people's health and diseases.

摘要

性别和社会性别是健康领域的重要变量,尽管它们在医学中的纳入过程非常缓慢。如果研究具有敏感性并能产生富有成效的性别和社会性别证据,那么这些结果应纳入临床实践指南。然而,文献表明临床实践指南中针对这些类别的篇幅很少。本系统综述通过基于三个来源的临床实践指南制定方法文件,即AGREE报告清单、GRADE手册和西班牙国家健康服务临床指南计划的《健康指南》,探讨性别和社会性别维度的相关性。研究结果表明,在生物医学方法中忽视性别和社会性别问题可能会导致继续忽略确实影响人们健康和疾病的生物和社会层面的相关证据。

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Representations of clinical practice guidelines and health equity in healthcare literature: An integrative review.医疗保健文献中临床实践指南与健康公平的呈现:一项综合综述。
J Nurs Scholarsh. 2023 Mar;55(2):506-520. doi: 10.1111/jnu.12847. Epub 2022 Nov 23.
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Clinical practice guidelines: The good, the bad, and the ugly.临床实践指南:优点、缺点与不足之处
Injury. 2023 May;54 Suppl 3:S26-S29. doi: 10.1016/j.injury.2022.01.047. Epub 2022 Feb 1.
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Considerations of sex and gender dimensions by research ethics committees: a scoping review.研究伦理委员会对性别考量的考虑:范围综述。
Int Health. 2022 Nov 1;14(6):554-561. doi: 10.1093/inthealth/ihab093.
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Sex and gender considerations in reporting guidelines for health research: a systematic review.报告健康研究指南中的性别考虑因素:系统评价。
Biol Sex Differ. 2021 Nov 20;12(1):62. doi: 10.1186/s13293-021-00404-0.
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The importance of achieving sex- and gender-based equity in clinical trials: a call to action.在临床试验中实现基于性别的公平性的重要性:行动呼吁。
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The injustice of unfit clinical practice guidelines in low-resource realities.不适合资源匮乏现实情况的临床实践指南的不公正性。
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