Yang Xiangzheng, Rao Jingshan, Shen Chaoyi, Lian Huan, Wang Da, Wu Di, Chen Kunsong
Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Key Laboratory of Ministry of Agriculture and Rural Affairs of Biology and Genetic Improvement of Horticultural Crops (Growth and Development), College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.
Jinan Fruit Research Institute, All China Federation of Supply and Marketing Cooperatives, Jinan 250014, China.
Foods. 2023 Dec 29;13(1):132. doi: 10.3390/foods13010132.
The preparation of active packaging loaded with antimicrobial, antioxidant, and other functional agents has become a hot topic for food preservation in recent years. In this field, active fiber films based on spinning methods have attracted the interest of researchers owing to their high specific surface area, high porosity, high loading capacity, and good controlled release capacity. In the present work, neatly arranged ethyl cellulose (EC)/polyvinyl-pyrrolidone (PVP) fibrous films loaded with natamycin as an antimicrobial agent were prepared by microfluidic spinning. The encapsulation efficiency of natamycin was more than 90% in each group and the loading increased with increasing natamycin content. According to the characterization results of the natamycin-loaded EC/PVP fibrous films, hydrogen bonding was formed between natamycin and EC and PVP in the fibrous films. Meanwhile, the water contact angle of the fibrous films was increased, suggesting the improved hydrophobicity of the films. In the in vitro bacterial inhibition experiments, the active fiber films loaded with natamycin showed good antimicrobial activity, which could significantly inhibit the growth of gray mold. In conclusion, N-EC/PVP fibrous films with antimicrobial activity prepared by microfluidic spinning showed good potential in the field of active packaging.
近年来，负载抗菌剂、抗氧化剂及其他功能剂的活性包装制备已成为食品保鲜领域的热门话题。在该领域，基于纺丝方法的活性纤维膜因其高比表面积、高孔隙率、高负载量及良好的控释能力而吸引了研究人员的关注。在本研究中，通过微流控纺丝制备了整齐排列的负载纳他霉素（一种抗菌剂）的乙基纤维素（EC）/聚乙烯吡咯烷酮（PVP）纤维膜。每组中纳他霉素的包封率均超过90%，且负载量随纳他霉素含量的增加而增加。根据负载纳他霉素的EC/PVP纤维膜的表征结果，纳他霉素与纤维膜中的EC和PVP之间形成了氢键。同时，纤维膜的水接触角增大，表明膜的疏水性得到改善。在体外抑菌实验中，负载纳他霉素的活性纤维膜表现出良好的抗菌活性，可显著抑制灰霉的生长。总之，通过微流控纺丝制备的具有抗菌活性的N-EC/PVP纤维膜在活性包装领域显示出良好的潜力。
