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营养筛查、肌肉减少症和身体成分对摄入、蛋白质和人体测量控制结果的影响及对住院患者临床转归的影响。

Influence of the Results of Control of Intakes, Proteins and Anthropometry Nutritional Screening, Sarcopenia and Body Composition on the Clinical Evolution of Hospitalized Patients.

机构信息

Endocrinology and Nutrition Department, Hospital Universitario Nuestra Señora de Candelaria, Ctra. Del Rosario 145, 38010 Santa Cruz de Tenerife, Spain.

Faculty of Health Sciences, University of La Laguna, Calle Padre Herrera, 38200 La Laguna, Spain.

出版信息

Nutrients. 2023 Dec 20;16(1):14. doi: 10.3390/nu16010014.

Abstract

(1) Background: Hospital malnutrition and sarcopenia are common in inpatients and are associated with worse prognosis. Our objective is to determine the association of the positivity of CIPA (Control of Intakes, Proteins and Anthropometry) nutrition screening tool and sarcopenia and evaluate its prognostic implications (length of stay, readmissions and mortality) as well as different components of body composition. (2) Methodology: Cross-sectional single-center study and prospective six months follow-up for prognostic variables. On admission, CIPA and EWGSOP2 criteria were assessed. (3) Results: Four hundred inpatients, a median of 65.71 years old and 83.6% with high comorbidity, were evaluated. In total, 34.8% had positive CIPA and 19.3% sarcopenia. Positive CIPA and sarcopenia had worse results in body composition (fat mass (FM), fat-free mass (FFM) and appendicular skeletal muscle mass index (ASMI)) and dynamometry. Positive CIPA is significantly associated with worse prognosis (mortality (OR = 1.99), readmissions (OR = 1.86) and length of stay (B = 0.19)). Positive CIPA and sarcopenia combined are associated with a tendency to higher mortality (OR = 2.1, = 0.088). Low hand grip strength (HGS) is significantly related to a higher length of stay (B = -0.12). (4) Conclusions: In hospitalized patients, malnutrition independently and combined with sarcopenia is associated with a worse prognosis but not body composition. Low HGS is related to a higher length of stay.

摘要

(1) 背景:住院患者中普遍存在营养不良和肌肉减少症,与预后较差有关。我们的目的是确定 CIPA(摄入量、蛋白质和人体测量控制)营养筛查工具的阳性与肌肉减少症的相关性,并评估其预后意义(住院时间、再入院和死亡率)以及身体成分的不同组成部分。(2) 方法:横断面单中心研究和前瞻性六个月预后变量随访。入院时,评估 CIPA 和 EWGSOP2 标准。(3) 结果:共评估了 400 名住院患者,中位年龄为 65.71 岁,83.6%患有高合并症。共有 34.8%的患者 CIPA 阳性,19.3%的患者存在肌肉减少症。CIPA 阳性和肌肉减少症的患者在身体成分(脂肪量(FM)、去脂体重(FFM)和四肢骨骼肌质量指数(ASMI))和握力测试方面的结果更差。CIPA 阳性与预后较差显著相关(死亡率(OR = 1.99)、再入院率(OR = 1.86)和住院时间(B = 0.19))。CIPA 阳性和肌肉减少症合并存在与较高死亡率的趋势相关(OR = 2.1, = 0.088)。低握力(HGS)与住院时间延长显著相关(B = -0.12)。(4) 结论:在住院患者中,营养不良独立存在,与肌肉减少症合并存在与预后较差相关,但与身体成分无关。低 HGS 与住院时间延长相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cce/10780303/7722af37ba98/nutrients-16-00014-g001.jpg

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