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全面的护理和教育可以改善持续性牛奶、鸡蛋或花生过敏儿童的营养和生长状况:一项营养状况五年随访研究。

Comprehensive Care and Education Can Improve Nutritional and Growth Outcomes in Children with Persistent Cow's Milk, Egg, or Peanut Allergies: A Five-Year Follow-Up Study of Nutritional Status.

机构信息

Department of Hospital Nutrition and Dietetics, University Children's Hospital, University Medical Center Ljubljana, Bohoričeva 20, 1000 Ljubljana, Slovenia.

Department of Allergology, Rheumatology and Clinical Immunology, University Children's Hospital, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.

出版信息

Nutrients. 2023 Dec 22;16(1):48. doi: 10.3390/nu16010048.

DOI:10.3390/nu16010048
PMID:38201880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10780307/
Abstract

BACKGROUND

Data suggest that food allergies greatly impact a child's health and growth due to inadequate nutrient intake. Our study aimed to establish the long-term outcome of children with food allergies compared to a control group.

METHODS

This study was a retrospective cohort study with longitudinal follow-up with a mean period of 4.85 years from the diagnosis to the last study visit. The patients' nutritional intake was assessed using a three-day food diary and analysed by a dietitian. Patients (61 boys and 33 girls, mean age 6.9 years) had a single food allergy including 21 patients with cow's milk, 34 with egg, and 39 with peanut allergies. The control group included 36 children (19 boys and 17 girls, mean age 8.03 years). Blood analysis was performed on all participants.

RESULTS

Data from our study showed that patients with cow's milk, egg or peanut allergies had normal growth and achieved catch-up growth from the diagnosis until the last study visit. In the cow's milk allergy group, the allergy was shown to affect calcium intake ( < 0.05), while egg and peanut allergies did not impact the dietary intake of nutrients. None of the investigated food allergies affected blood results ( < 0.05).

CONCLUSIONS

In the present study, we showed that single food allergies do not compromise growth in children if they are provided with appropriate support and that the affected children reach catch-up growth from the diagnosis.

摘要

背景

数据表明,由于摄入的营养不足,食物过敏极大地影响了儿童的健康和成长。我们的研究旨在比较食物过敏儿童与对照组的长期结果。

方法

这是一项回顾性队列研究,具有纵向随访,从诊断到最后一次研究访问的平均时间为 4.85 年。营养师使用三天食物日记评估患者的营养摄入量并进行分析。患者(61 名男孩和 33 名女孩,平均年龄 6.9 岁)患有单一食物过敏,包括 21 例牛奶过敏、34 例鸡蛋过敏和 39 例花生过敏。对照组包括 36 名儿童(19 名男孩和 17 名女孩,平均年龄 8.03 岁)。所有参与者均进行了血液分析。

结果

我们的研究数据表明,患有牛奶、鸡蛋或花生过敏的患者生长正常,并在诊断至最后一次研究访问期间实现了追赶生长。在牛奶过敏组中,过敏被证明会影响钙的摄入(<0.05),而鸡蛋和花生过敏不会影响营养素的饮食摄入。没有一种调查的食物过敏会影响血液结果(<0.05)。

结论

在本研究中,我们表明,如果为患有单一食物过敏的儿童提供适当的支持,他们的生长不会受到影响,并且受影响的儿童从诊断开始就会实现追赶生长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/e87ea4202ac5/nutrients-16-00048-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/782cad3131f0/nutrients-16-00048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/852e6854b2a2/nutrients-16-00048-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/513c9ff3742e/nutrients-16-00048-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/e87ea4202ac5/nutrients-16-00048-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/782cad3131f0/nutrients-16-00048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/852e6854b2a2/nutrients-16-00048-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/513c9ff3742e/nutrients-16-00048-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/10780307/e87ea4202ac5/nutrients-16-00048-g004.jpg

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本文引用的文献

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Personalized Nutrition Approach in Food Allergy: Is It Prime Time Yet?个性化营养方法在食物过敏中的应用:是否已到黄金时期?
Nutrients. 2019 Feb 9;11(2):359. doi: 10.3390/nu11020359.
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Nutritional Issues in Food Allergy.食物过敏中的营养问题。
Clin Rev Allergy Immunol. 2019 Oct;57(2):166-178. doi: 10.1007/s12016-018-8688-x.
4
Nutritional management of cow's milk allergy in children: An update.儿童牛奶蛋白过敏的营养管理:最新进展
Arch Pediatr. 2018 Apr;25(3):236-243. doi: 10.1016/j.arcped.2018.01.007. Epub 2018 Mar 22.
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The Role of Nutritional Aspects in Food Allergy: Prevention and Management.营养方面在食物过敏中的作用:预防和管理。
Nutrients. 2017 Aug 9;9(8):850. doi: 10.3390/nu9080850.
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The impact of the elimination diet on growth and nutrient intake in children with food protein induced gastrointestinal allergies.排除饮食对食物蛋白诱导的胃肠道过敏儿童生长及营养摄入的影响
Clin Transl Allergy. 2016 Jul 14;6:25. doi: 10.1186/s13601-016-0115-x. eCollection 2016.
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