Smithers-Sheedy Hayley, Waight Emma, Swinburn Katherine L, Given Fiona, Hooke Kate, Webb Annabel, McIntyre Sarah, Henry Georgina, Honan Ingrid
Cerebral Palsy Alliance Research Institute, Sydney Medical School, The University of Sydney, Camperdown, NSW 2050, Australia.
UTS Disability Research Network, University of Technology, Ultimo, NSW 2007, Australia.
J Clin Med. 2023 Dec 19;13(1):1. doi: 10.3390/jcm13010001.
Mindfulness-Based Stress Reduction (MBSR) has not yet been evaluated for people with cerebral palsy (CP). The aims of this randomised control trial were to investigate whether a modified telehealth MBSR program could improve mindfulness and reduce depression, anxiety, and emotion regulation difficulties among adults with CP with elevated anxiety and/or emotional regulation difficulties. Participants ( = 31) with elevated anxiety and/or emotion regulation difficulties and no/mild intellectual impairment were randomised to a modified telehealth MBSR program (90 min weekly, 9 weeks) group or a wait-list group. Measurements were collected prior to (T1), after (T2), and 8 weeks post-intervention (T3). The primary outcome was the mean between-group difference in the change in Cognitive and Affective Mindfulness Scale-R (CAMS-R) scores in T1-T2. The secondary outcomes included mean within-group differences over time for the CAMS-R total scores, Depression Anxiety and Stress Scale-21 subscales, and Difficulties in Emotion Regulation Scale (DERS) total t-score. We found no statistically significant between-group difference in mean change in mindfulness scores for T1-T2 (primary outcome). Secondary outcomes: The MBSR intervention group had improved CAMS-R scores with respect to T1-T2 and T1-T3; improved mean scores for Depression and Stress subscales for T1-T2; and improved DERS -scores for T1-T2 and T1-T3. In conclusion, this study found no significant between-group difference for the primary outcome of mindfulness. The MBSR program was successfully modified for adults with CP and was effective in improving depression, stress, and emotion regulation. ACTRN12621000960853.
基于正念减压疗法（MBSR）尚未针对脑瘫（CP）患者进行评估。这项随机对照试验的目的是调查一种改良的远程健康MBSR项目是否能够提高正念水平，并减轻焦虑、抑郁以及情绪调节困难，这些对象为焦虑水平升高和/或存在情绪调节困难的成年CP患者。焦虑水平升高和/或存在情绪调节困难且无/轻度智力障碍的参与者（n = 31）被随机分为改良的远程健康MBSR项目组（每周90分钟，共9周）或等待名单组。在干预前（T1）、干预后（T2）以及干预后8周（T3）收集测量数据。主要结局是T1 - T2期间认知与情感正念量表 - R（CAMS - R）得分变化的组间平均差异。次要结局包括CAMS - R总分、抑郁焦虑压力量表 - 21子量表以及情绪调节困难量表（DERS）总t分数随时间的组内平均差异。我们发现T1 - T2期间正念得分的组间平均变化没有统计学显著差异（主要结局）。次要结局：MBSR干预组在T1 - T2以及T1 - T3期间CAMS - R得分有所改善；在T1 - T2期间抑郁和压力子量表的平均得分有所改善；在T1 - T2以及T1 - T3期间DERS得分有所改善。总之，本研究发现正念这一主要结局在组间没有显著差异。MBSR项目成功针对成年CP患者进行了改良，并在改善抑郁、压力和情绪调节方面有效。澳大利亚新西兰临床试验注册中心编号：ACTRN12621000960853。
