The optimal design and construction of multispectral cameras can remarkably reduce the costs of spectral imaging systems and efficiently decrease the amount of image processing and analysis required. Also, multispectral imaging provides effective imaging information through higher-resolution images. This study aimed to develop novel, multispectral cameras based on Fabry-Pérot technology for agricultural applications such as plant/weed separation, ripeness estimation, and disease detection. Two multispectral cameras were developed, covering visible and near-infrared ranges from 380 nm to 950 nm. A monochrome image sensor with a resolution of 1600 × 1200 pixels was used, and two multispectral filter arrays were developed and mounted on the sensors. The filter pitch was 4.5 μm, and each multispectral filter array consisted of eight bands. Band selection was performed using a genetic algorithm. For VIS and NIR filters, maximum RMS values of 0.0740 and 0.0986 were obtained, respectively. The spectral response of the filters in VIS was significant; however, in NIR, the spectral response of the filters after 830 nm decreased by half. In total, these cameras provided 16 spectral images in high resolution for agricultural purposes.