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基于光子晶体耦合腔波导的高灵敏度无标记光学生物传感器设计

Design of a High -Factor Label-Free Optical Biosensor Based on a Photonic Crystal Coupled Cavity Waveguide.

作者信息

Jannesari Reyhaneh, Pühringer Gerald, Stocker Gerald, Grille Thomas, Jakoby Bernhard

机构信息

Institute for Microelectronics and Microsensors, Johannes Kepler University, 4040 Linz, Austria.

Infineon Technologies Austria AG, 9520 Villach, Austria.

出版信息

Sensors (Basel). 2023 Dec 28;24(1):193. doi: 10.3390/s24010193.

Abstract

In recent years, there has been a significant increase in research into silicon-based on-chip sensing. In this paper, a coupled cavity waveguide (CCW) based on a slab photonic crystal structure was designed for use as a label-free biosensor. The photonic crystal consisted of holes arranged in a triangular lattice. The incorporation of defects can be used to design sensor devices, which are highly sensitive to even slight alterations in the refractive index with a small quantity of analyte. The plane wave expansion method (PWE) was used to study the dispersion and profile of the CCW modes, and the finite difference time domain (FDTD) technique was used to study the transmission spectrum, quality factor, and sensitivity. We present an analysis of adiabatically coupling light into a coupled cavity waveguide. The results of the simulation indicated that a sensitivity of 203 nm/RIU and a quality factor of 13,360 could be achieved when the refractive indices were in the range of 1.33 to 1.55.

摘要

近年来,基于硅的片上传感研究有了显著增加。在本文中,设计了一种基于平板光子晶体结构的耦合腔波导(CCW)用作无标记生物传感器。光子晶体由排列成三角晶格的孔组成。引入缺陷可用于设计传感器器件,这些器件对少量分析物的折射率即使有微小变化也高度敏感。采用平面波展开法(PWE)研究CCW模式的色散和分布,采用时域有限差分(FDTD)技术研究传输光谱、品质因数和灵敏度。我们对光绝热耦合到耦合腔波导进行了分析。模拟结果表明,当折射率在1.33至1.55范围内时,灵敏度可达203 nm/RIU,品质因数可达13360。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82df/10781198/5ff4debf84bc/sensors-24-00193-g001.jpg

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