Barlough J E, Berry E S, Smith A W, Skilling D E
J Wildl Dis. 1987 Jan;23(1):45-51. doi: 10.7589/0090-3558-23.1.45.
Neutralizing antibodies to Tillamook calicivirus (TCV) were found in sera collected from California sea lions (Zalophus c. californianus Lesson) in 1983 and 1984 and in sera collected from Steller sea lions (Eumetopias jubatus Schreber) in 1976 and 1985. The combined prevalence of antibodies for these two species was 10/228 = 4.38%. Titers ranged from 1:20 (five animals), to 1:40 (four animals), to 1:80 (one animal) by standard microtiter neutralization assay. The seropositive pinnipeds were dispersed widely along the margins of the eastern Pacific rim, from the Bering Sea to the Santa Barbara Channel. Antibodies to TCV were not found in sera collected from northern fur seals (Callorhinus ursinus L.), Pacific walruses (Odobenus rosmarus divergens Illiger), seals of the family Phocidae, or several cetacean species. Tillamook calicivirus was isolated originally in 1981 from dairy calves in Oregon; the finding of neutralizing antibodies in two widely distributed species of sea lions suggests the possibility of a marine origin for this agent.
1983年和1984年从加利福尼亚海狮（Zalophus c. californianus Lesson）采集的血清中，以及1976年和1985年从北海狮（Eumetopias jubatus Schreber）采集的血清中发现了针对蒂拉穆克杯状病毒（TCV）的中和抗体。这两个物种抗体的综合流行率为10/228 = 4.38%。通过标准微量滴定中和试验，滴度范围从1:20（5只动物）到1:40（4只动物）再到1:80（1只动物）。血清反应阳性的鳍足类动物沿着东太平洋边缘广泛分布，从白令海到圣巴巴拉海峡。在从北海狗（Callorhinus ursinus L.）、太平洋海象（Odobenus rosmarus divergens Illiger）、海豹科海豹或几种鲸类动物采集的血清中未发现针对TCV的抗体。蒂拉穆克杯状病毒最初于1981年从俄勒冈州的奶牛犊中分离出来；在两种广泛分布的海狮物种中发现中和抗体表明这种病原体可能起源于海洋。
