Patel Daxkumar, Patel Kush, Parekh Shani, Ajwani Trisha, Patel Savan
Internal Medicine, Government Medical College Baroda, Vadodara, IND.
Medicine, Government Medical College Baroda, Vadodara, IND.
Cureus. 2023 Dec 5;15(12):e50011. doi: 10.7759/cureus.50011. eCollection 2023 Dec.
Dermatomyositis represents a rare autoimmune disorder characterized by the concurrent presentation of inflammatory myopathy and distinctive cutaneous manifestations. Herein, we present a comprehensive case report involving a 62-year-old male patient exhibiting a complex array of symptoms encompassing progressive muscle weakness, characteristic dermatological findings, and systemic involvement. This case report serves to illuminate the diagnostic intricacies inherent to dermatomyositis and underscore the imperative for a multidisciplinary approach to its effective management. The clinical presentation of the patient featured hallmark signs such as the classic heliotrope rash, Gottron's papules, and proximal muscle weakness, all indicative of dermatomyositis. Laboratory investigations revealed elevated muscle enzyme levels and the presence of positive autoantibodies, thereby reinforcing the diagnostic framework. Imaging modalities substantiated muscular involvement, while electromyography provided definitive evidence of myopathic alterations. Notably, a muscle biopsy further corroborated the diagnostic findings. In response to these diagnostic cues, the patient was expeditiously initiated on a therapeutic regimen encompassing corticosteroids, immunosuppressants, calcium channel blockers, and a tailored physical therapy program. This case underscores the pivotal significance of timely recognition and intervention for the treatment of dermatomyositis, thus mitigating the risk of long-term complications and enhancing the patient's overall quality of life. Moreover, it highlights the indispensability of interdisciplinary collaboration, uniting the expertise of dermatologists, rheumatologists, and neurologists, in navigating the intricacies of this intricate autoimmune disorder. We emphasize the pressing need for a comprehensive evaluation and an individualized therapeutic approach, thereby amplifying the prospects for superior patient outcomes and an improved quality of life.
皮肌炎是一种罕见的自身免疫性疾病，其特征为炎症性肌病和独特的皮肤表现同时出现。在此，我们报告一例综合病例，患者为一名62岁男性，表现出一系列复杂症状，包括进行性肌无力、典型的皮肤病学表现及全身受累。本病例报告旨在阐明皮肌炎固有的诊断复杂性，并强调采用多学科方法进行有效管理的必要性。患者的临床表现具有标志性体征，如典型的向阳疹、Gottron丘疹和近端肌无力，均提示皮肌炎。实验室检查显示肌酶水平升高及自身抗体阳性，从而强化了诊断依据。影像学检查证实了肌肉受累，而肌电图提供了肌病改变的确切证据。值得注意的是，肌肉活检进一步证实了诊断结果。基于这些诊断线索，迅速开始对患者进行治疗，治疗方案包括皮质类固醇、免疫抑制剂、钙通道阻滞剂及量身定制的物理治疗计划。本病例强调了及时识别和干预对皮肌炎治疗的关键意义，从而降低长期并发症风险并提高患者的整体生活质量。此外，它凸显了跨学科合作的必要性，皮肤科医生、风湿病学家和神经科医生需联合专业知识，以应对这种复杂自身免疫性疾病的复杂性。我们强调迫切需要进行全面评估和个体化治疗方法，从而增加实现更佳患者预后和改善生活质量的可能性。
