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类胡萝卜素在骨骼健康中的作用——一篇叙述性综述。

The role of carotenoids in bone health-A narrative review.

作者信息

Kulczyński Bartosz, Sidor Andrzej, Brzozowska Anna, Gramza-Michałowska Anna

机构信息

Department of Gastronomy Science and Functional Foods, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Poznań, Poland.

Department of Gastronomy Science and Functional Foods, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Poznań, Poland.

出版信息

Nutrition. 2024 Mar;119:112306. doi: 10.1016/j.nut.2023.112306. Epub 2023 Dec 1.

DOI:10.1016/j.nut.2023.112306
PMID:38211461
Abstract

Osteoporosis constitutes a serious challenge for public health. Dietary patterns belong to important, modifiable risk factors of this disease. Therefore, what and in what quantities we consume on a daily basis are extremely relevant. It is commonly known that bone health is positively affected by vitamins (e.g., vitamin D and vitamin K) as well as mineral components (e.g., calcium and magnesium). However, the human diet consists of many other groups of compounds that exhibit a potential antiosteoporotic and supporting bone-building effect. These dietary components include carotenoids. This paper presents a broad review of studies on the influence of particular carotenoids (β-carotene, lutein, zeaxanthin, β-cryptoxanthin, and lycopene) on bones. The paper discusses up-to-date in vitro experiments and research on animal models and presents how the results translate into clinical effect in humans.

摘要

骨质疏松症对公共卫生构成了严峻挑战。饮食模式是这种疾病重要的、可改变的风险因素。因此,我们日常的饮食内容及摄入量都极为重要。众所周知,维生素(如维生素D和维生素K)以及矿物质成分(如钙和镁)对骨骼健康有积极影响。然而,人类饮食还包含许多其他具有潜在抗骨质疏松和支持骨骼生成作用的化合物组。这些饮食成分包括类胡萝卜素。本文全面综述了关于特定类胡萝卜素(β-胡萝卜素、叶黄素、玉米黄质、β-隐黄质和番茄红素)对骨骼影响的研究。本文讨论了最新的体外实验和动物模型研究,并介绍了这些结果如何转化为对人类的临床效果。

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