• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

关键抗旱响应基因的优越单倍型为培育抗气候水稻品种提供了机会。

Superior haplotypes of key drought-responsive genes reveal opportunities for the development of climate-resilient rice varieties.

机构信息

International Rice Research Institute (IRRI), South-Asia Hub, Hyderabad, India.

International Rice Research Institute, South Asia Regional Centre (ISARC), Varanasi, India.

出版信息

Commun Biol. 2024 Jan 12;7(1):89. doi: 10.1038/s42003-024-05769-7.

DOI:10.1038/s42003-024-05769-7
PMID:38216712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10786901/
Abstract

Haplotype-based breeding is an emerging and innovative concept that enables the development of designer crop varieties by exploiting and exploring superior alleles/haplotypes among target genes to create new traits in breeding programs. In this regard, whole-genome re-sequencing of 399 genotypes (landraces and breeding lines) from the 3000 rice genomes panel (3K-RG) is mined to identify the superior haplotypes for 95 drought-responsive candidate genes. Candidate gene-based association analysis reveals 69 marker-trait associations (MTAs) in 16 genes for single plant yield (SPY) under drought stress. Haplo-pheno analysis of these 16 genes identifies superior haplotypes for seven genes associated with the higher SPY under drought stress. Our study reveals that the performance of lines possessing superior haplotypes is significantly higher (p ≤ 0.05) as measured by single plant yield (SPY), for the OsGSK1-H4, OsDSR2-H3, OsDIL1-H22, OsDREB1C-H3, ASR3-H88, DSM3-H4 and ZFP182-H4 genes as compared to lines without the superior haplotypes. The validation results indicate that a superior haplotype for the DREB transcription factor (OsDREB1C) is present in all the drought-tolerant rice varieties, while it was notably absent in all susceptible varieties. These lines carrying the superior haplotypes can be used as potential donors in haplotype-based breeding to develop high-yielding drought-tolerant rice varieties.

摘要

基于单倍型的育种是一种新兴的创新概念，它通过利用和探索目标基因中的优异等位基因/单倍型，在育种计划中创造新的性状，从而开发设计作物品种。在这方面，对来自 3000 个水稻基因组面板（3K-RG）的 399 个基因型（地方品种和育种种系）进行了全基因组重测序，以鉴定 95 个抗旱候选基因的优异单倍型。基于候选基因的关联分析揭示了 16 个基因中的 69 个标记-性状关联（MTAs），用于在干旱胁迫下的单株产量（SPY）。对这 16 个基因的单倍型-表型分析确定了 7 个与干旱胁迫下更高 SPY 相关的基因的优异单倍型。我们的研究表明，与不具有优异单倍型的系相比，具有优异单倍型的系的表现显著更高（p≤0.05），这是通过单株产量（SPY）来衡量的，这些系包括 OsGSK1-H4、OsDSR2-H3、OsDIL1-H22、OsDREB1C-H3、ASR3-H88、DSM3-H4 和 ZFP182-H4 基因。验证结果表明，耐旱水稻品种中存在 DREB 转录因子（OsDREB1C）的优异单倍型，而在所有易感品种中均未见该单倍型。这些携带优异单倍型的系可以作为基于单倍型的育种中的潜在供体，以开发高产耐旱水稻品种。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/7a1e7e0218ee/42003_2024_5769_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/e2b3e8257556/42003_2024_5769_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/af9f35992b19/42003_2024_5769_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/bc60b100ef6a/42003_2024_5769_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/7a1e7e0218ee/42003_2024_5769_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/e2b3e8257556/42003_2024_5769_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/af9f35992b19/42003_2024_5769_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/bc60b100ef6a/42003_2024_5769_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/10786901/7a1e7e0218ee/42003_2024_5769_Fig4_HTML.jpg

相似文献

1
Superior haplotypes of key drought-responsive genes reveal opportunities for the development of climate-resilient rice varieties.关键抗旱响应基因的优越单倍型为培育抗气候水稻品种提供了机会。
Commun Biol. 2024 Jan 12;7(1):89. doi: 10.1038/s42003-024-05769-7.
2
Superior haplotypes for haplotype-based breeding for drought tolerance in pigeonpea (Cajanus cajan L.).基于单倍型的耐旱性 pigeonpea（Cajanus cajan L.）选育的优势单倍型。
Plant Biotechnol J. 2020 Dec;18(12):2482-2490. doi: 10.1111/pbi.13422. Epub 2020 Jun 22.
3
Superior haplotypes towards development of low glycemic index rice with preferred grain and cooking quality.具有优选谷物和烹饪品质的低血糖指数大米的优异单倍型。
Sci Rep. 2021 May 12;11(1):10082. doi: 10.1038/s41598-021-87964-8.
4
Haplotype analysis of key genes governing grain yield and quality traits across 3K RG panel reveals scope for the development of tailor-made rice with enhanced genetic gains.对 3K RG 面板中控制产量和品质性状的关键基因进行单体型分析，揭示了开发具有增强遗传增益的定制化水稻的潜力。
Plant Biotechnol J. 2019 Aug;17(8):1612-1622. doi: 10.1111/pbi.13087. Epub 2019 Feb 15.
5
From QTL to variety-harnessing the benefits of QTLs for drought, flood and salt tolerance in mega rice varieties of India through a multi-institutional network.从 QTL 到品种——通过多机构网络利用印度巨型水稻品种对干旱、洪水和耐盐性的 QTL 优势。
Plant Sci. 2016 Jan;242:278-287. doi: 10.1016/j.plantsci.2015.08.008. Epub 2015 Aug 20.
6
Genetic diversity for drought and low-phosphorus tolerance in rice (Oryza sativa L.) varieties and donors adapted to rainfed drought-prone ecologies.适应雨养干旱生态系统的水稻品种和供体的耐旱和耐低磷遗传多样性。
Sci Rep. 2021 Jul 1;11(1):13671. doi: 10.1038/s41598-021-93325-2.
7
Identification of genomic regions governing moisture and heat stress tolerance employing association mapping in rice (Oryza sativa L.).利用关联作图在水稻（Oryza sativa L.）中鉴定水分和热应激耐性的基因组区域。
Mol Biol Rep. 2023 Feb;50(2):1499-1515. doi: 10.1007/s11033-022-08153-y. Epub 2022 Dec 12.
8
Identification of Superior Haplotypes and Haplotype Combinations for Grain Size- and Weight-Related Genes for Breeding Applications in Rice ( L.).鉴定水稻粒重相关基因的优势单倍型及其组合，用于水稻的育种应用。
Genes (Basel). 2023 Dec 12;14(12):2201. doi: 10.3390/genes14122201.
9
Candidate Genes and Pathways in Rice Co-Responding to Drought and Salt Identified by gcHap Network.通过 gcHap 网络鉴定的水稻响应干旱和盐胁迫的候选基因和途径。
Int J Mol Sci. 2022 Apr 5;23(7):4016. doi: 10.3390/ijms23074016.
10
SSR marker-based genetic diversity analysis and SNP haplotyping of genes associating abiotic and biotic stress tolerance, rice growth and development and yield across 93 rice landraces.基于 SSR 标记的遗传多样性分析和 SNP 单倍型分析，这些基因与非生物和生物胁迫耐受性、水稻生长发育和产量有关，研究对象为 93 份水稻地方品种。
Mol Biol Rep. 2021 Aug;48(8):5943-5953. doi: 10.1007/s11033-021-06595-4. Epub 2021 Jul 28.

引用本文的文献

1
An Australian chickpea pan-genome provides insights into genome organization and offers opportunities for enhancing drought adaptation for crop improvement.一个澳大利亚鹰嘴豆泛基因组有助于深入了解基因组组织，并为增强作物抗旱适应性以促进作物改良提供了机会。
Plant Biotechnol J. 2025 Jun 18. doi: 10.1111/pbi.70192.
2
Genome-wide association analysis in identification of superior haplotypes for vegetative stage drought stress tolerance in rice.全基因组关联分析在鉴定水稻营养生长期耐旱性优良单倍型中的应用
Physiol Mol Biol Plants. 2025 Mar;31(3):435-452. doi: 10.1007/s12298-025-01573-7. Epub 2025 Mar 23.
3
Integration of ATAC-seq and RNA-seq reveals the dynamics of chromatin accessibility and gene expression in zoysiagrass response to drought.

本文引用的文献

1
A transcriptional regulator that boosts grain yields and shortens the growth duration of rice.一种能提高水稻产量并缩短其生长周期的转录调控因子。
Science. 2022 Jul 22;377(6604):eabi8455. doi: 10.1126/science.abi8455.
2
Drought Tolerant Near Isogenic Lines of Pusa 44 Pyramided With and , Show Accelerated Recovery Response in a High Throughput Phenomics Based Phenotyping.与干旱耐受性相关的近等基因系Pusa 44与[具体基因名称未给出]和[具体基因名称未给出]聚合，在基于高通量表型组学的表型分析中显示出加速的恢复反应。
Front Plant Sci. 2022 Jan 5;12:752730. doi: 10.3389/fpls.2021.752730. eCollection 2021.
3
Marker-assisted forward and backcross breeding for improvement of elite Indian rice variety Naveen for multiple biotic and abiotic stress tolerance.
ATAC-seq与RNA-seq的整合揭示了结缕草对干旱响应中染色质可及性和基因表达的动态变化。
Plant Cell Rep. 2025 Apr 1;44(4):92. doi: 10.1007/s00299-025-03469-y.
4
Identifying Heat Adaptability QTLs and Candidate Genes for Grain Appearance Quality at the Flowering Stage in Rice.鉴定水稻开花期外观品质的热适应性QTL和候选基因。
Rice (N Y). 2025 Mar 11;18(1):13. doi: 10.1186/s12284-025-00770-y.
5
Rice homolog of Arabidopsis Xylem NAC domain 1 (OsXND1), a NAC transcription factor regulates drought stress responsive root system architecture in indica rice.拟南芥木质部 NAC 结构域蛋白 1（Arabidopsis Xylem NAC domain 1，AtXND1）的水稻同源基因 OsXND1（Rice homolog of Arabidopsis Xylem NAC domain 1，OsXND1）是一个 NAC 转录因子，它调节籼稻对干旱胁迫的根系形态建成反应。
Mol Genet Genomics. 2024 Oct 6;299(1):94. doi: 10.1007/s00438-024-02178-7.
利用标记辅助正向和反向回交选育改良印度优质水稻品种 Naveen 的多种生物和非生物胁迫耐受性。
PLoS One. 2021 Sep 2;16(9):e0256721. doi: 10.1371/journal.pone.0256721. eCollection 2021.
4
Molecular Breeding for Improving Productivity of L. cv. Pusa 44 under Reproductive Stage Drought Stress through Introgression of a Major QTL, .利用导入一个主要 QTL ，通过分子育种提高 L. cv. Pusa 44 在生殖阶段干旱胁迫下的生产力。
Genes (Basel). 2021 Jun 24;12(7):967. doi: 10.3390/genes12070967.
5
Genomics and breeding innovations for enhancing genetic gain for climate resilience and nutrition traits.基因组学和育种创新，以提高对气候适应性和营养特性的遗传增益。
Theor Appl Genet. 2021 Jun;134(6):1829-1843. doi: 10.1007/s00122-021-03847-6. Epub 2021 May 20.
6
Superior haplotypes towards development of low glycemic index rice with preferred grain and cooking quality.具有优选谷物和烹饪品质的低血糖指数大米的优异单倍型。
Sci Rep. 2021 May 12;11(1):10082. doi: 10.1038/s41598-021-87964-8.
7
Genomics Analyses Reveal Unique Classification, Population Structure and Novel Allele of Neo-Tetraploid Rice.基因组学分析揭示了新四倍体水稻的独特分类、群体结构和新等位基因。
Rice (N Y). 2021 Feb 6;14(1):16. doi: 10.1186/s12284-021-00459-y.
8
Status and prospects of genome-wide association studies in plants.植物全基因组关联研究的现状与展望。
Plant Genome. 2021 Mar;14(1):e20077. doi: 10.1002/tpg2.20077. Epub 2021 Jan 13.
9
Genetic gain for rice yield in rainfed environments in India.印度雨养环境下水稻产量的遗传增益。
Field Crops Res. 2021 Jan 1;260:107977. doi: 10.1016/j.fcr.2020.107977.
10
Marker-assisted breeding to develop the drought-tolerant version of Sabitri, a popular variety from Nepal.利用标记辅助育种培育尼泊尔流行品种萨比特里的耐旱版本。
Euphytica. 2017;213:184. doi: 10.1007/s10681-017-1976-3. Epub 2017 Jul 24.