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一项随机对照试验研究了低热量饮食控制高血压(DASH)方案对袖状胃切除术后 2 年体重反弹患者的人体测量学和血糖指标的影响。

A Randomized Controlled Trial Investigating the Impact of a Low-Calorie Dietary Approach to Stop Hypertension (DASH) on Anthropometric and Glycemic Measures in Patients Experiencing Weight Regain 2 Years Post Sleeve Surgery.

机构信息

Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Sports Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Obes Surg. 2024 Mar;34(3):892-901. doi: 10.1007/s11695-024-07057-z. Epub 2024 Jan 13.

DOI:10.1007/s11695-024-07057-z
PMID:38217832
Abstract

PURPOSE

To evaluate the effect of a low-calorie dietary approach to stop hypertension (DASH) compared to a low-calorie diet on weight control, body composition and glycemic measures in post sleeve patients with weight regain.

MATERIALS AND METHODS

Participants were randomly allocated to either the low-calorie DASH diet group (intervention) or the low-calorie diet group (control) for a duration of 16 weeks. Both groups had a prescribed caloric intake of 1000-1200 calories. The DASH diet group made dietary adjustments in accordance with the DASH pattern.

RESULTS

At the end of the study, both interventions significantly reduced anthropometric and body composition parameters (P-value < 0.001), with a greater decrease observed in the low-calorie DASH diet group (P-value < 0.001). Insulin levels and homeostatic model assessment for insulin resistance (HOMA-IR) decreased significantly in both groups, but the magnitude of these changes was not statistically different between the two groups. After adjusting for confounders, a significant difference was observed in post-intervention values and changes in weight, body mass index, and fat mass and fat-free mass.

CONCLUSION

In summary, adhering to a calorie-restricted DASH diet for 16 weeks improved weight loss, body mass index, and fat mass reduction in post-bariatric patients who experienced weight regain 2 years after surgery, compared to a calorie-restricted control diet. However, there was no significant difference in the effect on blood glucose, insulin, and HOMA-IR between the two diets.

摘要

目的

评估低热量膳食方法(DASH)对控制体重、身体成分和血糖指标的影响,与低热量饮食相比,在袖状胃切除术后体重反弹的患者中。

材料和方法

参与者被随机分配到低热量 DASH 饮食组(干预组)或低热量饮食组(对照组),持续 16 周。两组的热量摄入均为 1000-1200 卡路里。DASH 饮食组根据 DASH 模式进行饮食调整。

结果

研究结束时,两种干预措施均显著降低了人体测量和身体成分参数(P 值<0.001),低热量 DASH 饮食组的降幅更大(P 值<0.001)。两组的胰岛素水平和胰岛素抵抗稳态模型评估(HOMA-IR)均显著降低,但两组之间这些变化的幅度没有统计学差异。调整混杂因素后,干预后体重、体重指数、体脂和去脂体重的变化值和变化有显著差异。

结论

总之,与低热量对照饮食相比,坚持 16 周的热量限制 DASH 饮食可改善 2 年后手术体重反弹的肥胖症患者的体重减轻、体重指数和体脂减少,但两种饮食对血糖、胰岛素和 HOMA-IR 的影响无显著差异。

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