Kokmen E, Offord K P, Okazaki H
Neurology. 1987 Mar;37(3):426-30. doi: 10.1212/wnl.37.3.426.
The clinical records and autopsy protocols were studied from 350 cases in which an autopsy was done in Olmsted County, MN, in 1980 and 1981. Overall autopsy rate was 33.6%, and autopsy rate for those aged 60 years or more was 29%. Preselected criteria were used for diagnosis of dementia. Thirty-two demented and 68 nondemented patients had complete autopsies; all were more than 60 years old. Twenty-three of 32 (72%) demented patients had Alzheimer's disease. The frequency of cerebral infarcts among the nondemented patients was significantly higher than among the demented patients (p = 0.02).
对明尼苏达州奥姆斯特德县1980年和1981年进行尸检的350例病例的临床记录和尸检方案进行了研究。总体尸检率为33.6%，60岁及以上人群的尸检率为29%。采用预先选定的标准诊断痴呆症。32例痴呆患者和68例非痴呆患者进行了完整的尸检；所有患者均超过60岁。32例痴呆患者中有23例（72%）患有阿尔茨海默病。非痴呆患者中脑梗死的发生率显著高于痴呆患者（p = 0.02）。
