Sluss T K, Gruenberg E M, Rabins P, Kramer M
Neuropsychobiology. 1982;8(2):109-12. doi: 10.1159/000117884.
The distribution of signs indicative of localized brain damage important in the diagnosis of multi-infarct dementia (MD) has not been specified. The demented members of a longitudinally examined research panel (n = 519) were identified. Differential diagnosis of the probable causes of the dementias was made. Focal signs were found to occur in both the cases diagnosed as MID (n = 13) and the case diagnosed as senile dementia - Alzheimer's type (n = 27). It is important for the clinician in the evaluation of focal signs in dementing illness to consider the developmental sequence and the total clinical context of the disorder.
对多梗死性痴呆(MD)诊断具有重要意义的局灶性脑损伤体征分布尚未明确。在一个经过纵向研究的研究小组(n = 519)中识别出了痴呆患者。对痴呆的可能病因进行了鉴别诊断。结果发现,在诊断为多发性梗死性痴呆(MID,n = 13)的病例以及诊断为老年性痴呆 - 阿尔茨海默型(n = 27)的病例中均出现了局灶性体征。临床医生在评估痴呆症中的局灶性体征时,考虑疾病的发展顺序和整体临床背景非常重要。