老年人痴呆鉴别诊断中的心肌梗死

Myocardial infarction in the differential diagnosis of dementias in the elderly.

作者信息

Hontela S, Schwartz G

出版信息

J Am Geriatr Soc. 1979 Mar;27(3):104-6. doi: 10.1111/j.1532-5415.1979.tb04136.x.

DOI:10.1111/j.1532-5415.1979.tb04136.x

Abstract

The incidence of cerebral lesions in relation to myocardial infarction (MI) was evaluated on the basis of data obtained from medical records and autopsy reports on 269 psychogeriatric patients, in a 13-year retrospective study. Among 84 demented patients with MI, brain infarcts and hemorrhages were found in 42 percent, and Alzheimer's disease in 17 percent; (combination in 8 percent). In contrast, among 70 demented patients without MI, brain infarcts and hemorrhages were found in 11 percent, and Alzheimer's disease in 43 percent; (combination in 6 percent). Therefore, when it is difficult to differentiate senile dementia (Alzheimer's disease) from dementia due to cerebrovascular impairment, data on the presence or absence of myocardial infarction may prove useful.

摘要

在一项为期13年的回顾性研究中，基于从269名老年精神科患者的病历和尸检报告中获得的数据，评估了与心肌梗死（MI）相关的脑损伤发生率。在84名患有MI的痴呆患者中，发现脑梗死和出血的占42%，患阿尔茨海默病的占17%；（两者合并的占8%）。相比之下，在70名未患MI的痴呆患者中，发现脑梗死和出血的占11%，患阿尔茨海默病的占43%；（两者合并的占6%）。因此，当难以区分老年痴呆（阿尔茨海默病）和脑血管损伤所致痴呆时，有无心肌梗死的数据可能会有所帮助。