Institute of General Practice/Family Medicine, Philipps-University of Marburg, Marburg, Germany.
Department of Human Medicine, Institute of General Practice and Family Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
BMC Geriatr. 2024 Jan 15;24(1):60. doi: 10.1186/s12877-024-04672-4.
Regular physical activity has multiple health benefits, especially in older people. Therefore, the World Health Organization recommends at least 2.5 h of moderate physical activity per week. The aim of the POWER Study was to investigate whether volunteer-assisted walking improves the physical performance and health of older people.
We approached people aged 65 years and older with restricted mobility due to physical limitations and asked them to participate in this multicentre randomised controlled trial. The recruitment took place in nursing homes and the community setting. Participants randomly assigned to the intervention group were accompanied by volunteer companions for a 30-50 min walk up to three times a week for 6 months. Participants in the control group received two lectures that included health-related topics. The primary endpoint was physical function as measured with the Short Physical Performance Battery (SPPB) at baseline and 6 and 12 months. The secondary and safety endpoints were quality of life (EQ-5D-5L), fear of falling (Falls Efficacy Scale), cognitive executive function (the Clock Drawing Test), falls, hospitalisations and death.
The sample comprised 224 participants (79% female). We failed to show superiority of the intervention with regard to physical function (SPPB) or other health outcomes in the intention-to-treat analyses. However, additional exploratory analyses suggest benefits in those who undertook regular walks. The intervention appears to be safe regarding falls.
Regular physical activity is essential to preserve function and to improve health and quality of life. Against the background of a smaller-than-planned sample size, resulting in low power, and the interference of the COVID-19 pandemic, we suggest that community based low-threshold interventions deserve further exploration.
The trial was registered with the German Clinical Trials Register ( www.germanctr.de ), with number DRKS00015188 on 31/08/2018.
有规律的身体活动对健康有多种益处,尤其是对老年人。因此,世界卫生组织建议每周至少进行 2.5 小时的适度身体活动。POWER 研究的目的是调查志愿者辅助行走是否能改善老年人的身体机能和健康。
我们邀请了因身体限制而行动受限的 65 岁及以上的老年人参与这项多中心随机对照试验。招募工作在养老院和社区进行。随机分配到干预组的参与者由志愿者同伴陪同,每周进行 3 次,每次 30-50 分钟的散步,持续 6 个月。对照组的参与者接受了两次包括健康相关主题的讲座。主要终点是基线和 6 个月及 12 个月时用简短身体表现电池(SPPB)测量的身体功能。次要和安全性终点是生活质量(EQ-5D-5L)、跌倒恐惧(跌倒效能量表)、认知执行功能(时钟绘制测试)、跌倒、住院和死亡。
样本包括 224 名参与者(79%为女性)。在意向治疗分析中,我们未能显示干预对身体功能(SPPB)或其他健康结果的优越性。然而,额外的探索性分析表明,对于那些经常散步的人有好处。干预在跌倒方面似乎是安全的。
有规律的身体活动对于保持功能和改善健康和生活质量至关重要。考虑到计划样本量较小,导致效力较低,以及 COVID-19 大流行的干扰,我们建议进一步探索基于社区的低门槛干预措施。
该试验在德国临床试验注册中心(www.germanctr.de)注册,注册号为 DRKS00015188,于 2018 年 8 月 31 日注册。