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红参对神经退行性疾病中神经炎症的影响。

Effects of Red ginseng on neuroinflammation in neurodegenerative diseases.

作者信息

Lee Min Yeong, Kim Mikyung

机构信息

Department of Chemistry & Life Science, Sahmyook University, Hwarangro 815, Nowongu, Seoul, Republic of Korea.

Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Hwarangro 815, Nowongu, Seoul, Republic of Korea.

出版信息

J Ginseng Res. 2024 Jan;48(1):20-30. doi: 10.1016/j.jgr.2023.08.003. Epub 2023 Aug 29.

Abstract

Red ginseng (RG) is widely used as a herbal medicine. As the human lifespan has increased, numerous diseases have developed, and RG has also been used to treat various diseases. Neurodegenerative diseases are major problems that modern people face through their lives. Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are featured by progressive nerve system damage. Recently, neuroinflammation has emerged as a degenerative factor and is an immune response in which cytokines with nerve cells that constitute the nervous system. RG, a natural herbal medicine with fewer side effects than chemically synthesized drugs, is currently in the spotlight. Therefore, we reviewed studies reporting the roles of RG in treating neuroinflammation and neurodegenerative diseases and found that RG might help alleviate neurodegenerative diseases by regulating neuroinflammation.

摘要

红参(RG)作为一种草药被广泛使用。随着人类寿命的延长,多种疾病不断出现,红参也被用于治疗各种疾病。神经退行性疾病是现代人一生面临的主要问题。包括阿尔茨海默病、帕金森病、亨廷顿病和肌萎缩侧索硬化症在内的神经退行性疾病,其特征是神经系统进行性损伤。近年来,神经炎症已成为一种退行性因素,是一种由构成神经系统的神经细胞分泌细胞因子引发的免疫反应。红参作为一种副作用比化学合成药物少的天然草药,目前备受关注。因此,我们回顾了有关红参在治疗神经炎症和神经退行性疾病中作用的研究,发现红参可能通过调节神经炎症来帮助缓解神经退行性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e628/10785270/bd1950093cce/ga1.jpg

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