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早期缺血性坏死治疗策略的全面综述

A Comprehensive Review of Treatment Strategies for Early Avascular Necrosis.

作者信息

Lohiya Ashutosh, Dhaniwala Nareshkumar, Dudhekar Ulhas, Goyal Saksham, Patel Siddharth K

机构信息

Department of Orthopaedics and Traumatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

出版信息

Cureus. 2023 Dec 14;15(12):e50510. doi: 10.7759/cureus.50510. eCollection 2023 Dec.

Abstract

Avascular necrosis (AVN), characterised by compromised blood supply leading to bone necrosis, poses a significant challenge in orthopaedic and rheumatologic practice. This review comprehensively examines early AVN treatment strategies, including aetiology and risk factors, clinical presentation, conservative and surgical approaches, emerging therapies, and rehabilitation. Key findings underscore the importance of early detection, personalised treatment plans, and a multidisciplinary approach involving orthopaedic specialists, rheumatologists, and physical therapists. The implications for clinical practice emphasise individualised care, staying abreast of emerging therapies, and patient education. Recommendations for future management strategies highlight the need for imaging technology advancements, regenerative therapies integration, and ongoing research into genetic and molecular pathways. As the field continues to evolve, translating research findings into clinical practice holds promise for improving outcomes and enhancing the overall quality of life for individuals affected by AVN.

摘要

缺血性坏死(AVN),其特征是血液供应受损导致骨坏死,在骨科和风湿病学实践中构成了重大挑战。本综述全面研究了早期AVN的治疗策略,包括病因和危险因素、临床表现、保守和手术方法、新兴疗法以及康复。主要研究结果强调了早期检测、个性化治疗计划以及由骨科专家、风湿病学家和物理治疗师组成的多学科方法的重要性。对临床实践的影响强调了个性化护理、紧跟新兴疗法以及患者教育。未来管理策略的建议突出了成像技术进步、整合再生疗法以及对基因和分子途径进行持续研究的必要性。随着该领域的不断发展,将研究结果转化为临床实践有望改善治疗效果并提高受AVN影响个体的整体生活质量。

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