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一名在儿童期接受尤因肉瘤治疗后骨盆发育不全且受过放疗的患者出现慢性腹主动脉闭塞。

Chronic abdominal aortic occlusion in a patient with an underdeveloped, irradiated pelvis after childhood treatment of Ewing Sarcoma.

作者信息

Will Jack A, Bindi Jonathan M, Crawford John L, West Charles A, Deitch Johnathan S

机构信息

Division of Vascular Surgery, TCU Burnett School of Medicine, Texas Health Harris Methodist Hospital, Fort Worth, TX.

Department of Surgery, Texas Health Harris Methodist Hospital, Fort Worth, TX.

出版信息

J Vasc Surg Cases Innov Tech. 2023 Nov 26;10(1):101380. doi: 10.1016/j.jvscit.2023.101380. eCollection 2024 Feb.

DOI:10.1016/j.jvscit.2023.101380
PMID:38226318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10788263/
Abstract

Chronic radiation-induced arterial injury is generally predictable by known tumor types and anatomic location. We present the first case of radiation-induced chronic aortic occlusion associated with a small pelvis secondary to the treatment of childhood Ewing sarcoma. The patient presented with profound claudication and accelerated atherosclerosis obliterans of the aortoiliac system and failed endovascular treatment. Successful aortic reconstruction was performed. This case highlights the long-term effects of chemoradiation to the aortoiliac segment and pelvic bones in a child, and the technical challenges of vascular reconstruction in an underdeveloped irradiated pelvis.

摘要

慢性辐射诱导的动脉损伤通常可根据已知的肿瘤类型和解剖位置进行预测。我们报告了首例因儿童尤因肉瘤治疗继发的与小骨盆相关的辐射诱导慢性主动脉闭塞病例。该患者出现严重跛行以及腹主动脉-髂动脉系统加速性动脉粥样硬化闭塞,血管内治疗失败。成功实施了主动脉重建术。该病例突出了放化疗对儿童腹主动脉-髂动脉段和骨盆骨骼的长期影响,以及在发育不全的受辐射骨盆中进行血管重建的技术挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/477366518684/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/d6013c96908e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/9243fbfcd909/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/2b7ac5b0096b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/244ec3728944/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/477366518684/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/d6013c96908e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/9243fbfcd909/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/2b7ac5b0096b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/244ec3728944/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3464/10788263/477366518684/gr5.jpg

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本文引用的文献

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Endovascular interventions for claudication do not meet minimum standards for the Society for Vascular Surgery efficacy guidelines.血管内介入治疗跛行不符合血管外科学会疗效指南的最低标准。
J Vasc Surg. 2021 May;73(5):1693-1700.e3. doi: 10.1016/j.jvs.2020.10.067. Epub 2020 Nov 27.
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Pathology of radiation induced heart disease.放射性心脏病的病理学
Rep Pract Oncol Radiother. 2020 Mar-Apr;25(2):178-181. doi: 10.1016/j.rpor.2019.12.015. Epub 2019 Dec 17.
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Pelvic radiation therapy: Between delight and disaster.盆腔放射治疗:介于喜悦与灾难之间。
World J Gastrointest Surg. 2015 Nov 27;7(11):279-88. doi: 10.4240/wjgs.v7.i11.279.
4
Diagnosis and treatment of Ewing sarcoma of the bone: a review article.骨尤因肉瘤的诊断与治疗:一篇综述文章。
J Orthop Sci. 2015 Mar;20(2):250-63. doi: 10.1007/s00776-014-0687-z. Epub 2015 Feb 19.
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A contemporary experience of open aortic reconstruction in patients with chronic atherosclerotic occlusion of the abdominal aorta.慢性粥样硬化性腹主动脉闭塞患者的开放主动脉重建的当代体验。
J Vasc Surg. 2010 Nov;52(5):1164-72. doi: 10.1016/j.jvs.2010.05.112. Epub 2010 Aug 21.
6
Ewing's sarcoma of the ilium mimicking inflammatory arthritis of the hip: a case report.误诊为髋关节炎性关节炎的髂骨尤因肉瘤:一例报告
Cases J. 2009 Jun 29;2:6487. doi: 10.4076/1757-1626-2-6487.
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Radiation-induced peripheral artery disease.放射性外周动脉疾病
Catheter Cardiovasc Interv. 2008 Oct 1;72(4):563-8. doi: 10.1002/ccd.21681.
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Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II).外周动脉疾病管理的跨学会共识(TASC II)
Eur J Vasc Endovasc Surg. 2007;33 Suppl 1:S1-75. doi: 10.1016/j.ejvs.2006.09.024. Epub 2006 Nov 29.
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