Wells T R, Landing B H, Sandhu M, Lipsey A I
Pediatr Pathol. 1986;6(2-3):301-7. doi: 10.3109/15513818609037720.
That branched eccrine sweat glands occur has rarely been mentioned in the literature, and their incidence has never been determined. All eccrine glands in 0.5-cm2 pieces of anterior trunk skin of 59 children were microdissected, and the total number of glands and the number of branched eccrine glands determined. One-hundred fourteen of 17,539 (0.65%) were branched, 90% in the middermis and 10% at the epidermis. The apparently normal anatomic property that almost 1% of eccrine sweat glands are branched has not hitherto been appreciated. One doubly branched gland was found. Patients with leukemia (11 in the study) possibly had more branched glands than nonleukemic patients of the same body size. The best statistical relation of the number of sweat glands per unit area of skin (GUA) to surface area (SA) or age in children was the natural logarithm of GUA versus the reciprocal of surface area: LnGUA = (0.2205 X 1/SA) + 5.42. This result is consistent with the classical proposition that there is no important degree of formation of new eccrine glands, nor of loss, after birth, the density of glands per unit area of skin reducing as SA rises with growth during childhood.
文献中很少提及有分支的小汗腺的存在，其发生率也从未被确定过。对59名儿童躯干前部皮肤0.5平方厘米切片中的所有小汗腺进行显微解剖，确定腺体总数和有分支的小汗腺数量。在17539个腺体中有114个（0.65%）有分支，其中90%位于真皮中层，10%位于表皮。几乎1%的小汗腺有分支这一明显正常的解剖学特征迄今尚未被认识到。发现了一个双分支腺体。白血病患者（本研究中有11例）可能比相同体型的非白血病患者有更多有分支的腺体。儿童皮肤单位面积汗腺数量（GUA）与表面积（SA）或年龄的最佳统计关系是GUA的自然对数与表面积的倒数：LnGUA =（0.2205×1/SA）+5.42。这一结果与经典观点一致，即出生后新的小汗腺形成或消失的程度都不显著，随着儿童时期生长表面积增加，单位皮肤面积腺体密度降低。
