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胃旁路吻合口与袖状胃切除术术后一年的营养结果比较。

Nutritional Outcomes One Year after One Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy.

机构信息

Institute of Biochemistry, Food and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University of Jerusalem, Rehovot 76100, Israel.

Department of Surgery, Hadassah University Hospital Mount Scopusand, the Hebrew University-Hadassah Medical School, Jerusalem 91240, Israel.

出版信息

Nutrients. 2022 Jun 23;14(13):2597. doi: 10.3390/nu14132597.

Abstract

One Anastomosis Gastric Bypass (OAGB) and Sleeve Gastrectomy (SG) are the most common bariatric procedures performed worldwide. SG is a restrictive procedure whereas OAGB involves malabsorption as well, supposing a risk of deficiency development post OAGB. The aim of the study was to compare nutritional deficiencies and metabolic markers one year after the procedures, while adhering to the current protocols. Retrospective analysis was performed for data on 60 adults undergoing primary OAGB, compared to 60 undergoing primary SG. Mean pre-surgery BMI for SG was 42.7 kg/m and 43.3 kg/m for OAGB. A multidisciplinary team followed up with the patients at least 3 times during the first year. Mean weight loss was 39.0 kg for SG and 44.1 kg for OAGB. The OAGB group presented a significantly sharper decline in T.Chol and a trend for sharper LDL decrease; a higher increase in folate and a trend for a greater decrease in albumin and hemoglobin were observed in OAGB. For vitamin B12, D, iron and ferritin, no difference was observed between the treatment groups, although there were some in-group differences. Nutritional recommendations and adopted supplement plans minimize the risk of deficiencies and result in improvement in metabolic biomarkers one year after OAGB, which was comparable to SG.

摘要

一种吻合胃旁路术(OAGB)和袖状胃切除术(SG)是目前全球最常见的两种减重手术。SG 是一种限制型手术,而 OAGB 也涉及吸收不良,假设 OAGB 术后会有发展缺陷的风险。本研究的目的是比较两种手术后一年的营养缺乏和代谢标志物,并遵循当前的治疗方案。对 60 例接受初次 OAGB 和 60 例接受初次 SG 的成年人的数据进行回顾性分析。SG 的术前平均 BMI 为 42.7kg/m,OAGB 为 43.3kg/m。多学科团队在第一年至少对患者进行了 3 次随访。SG 的平均减重为 39.0kg,OAGB 为 44.1kg。OAGB 组的 T.Chol 下降幅度明显更大,LDL 下降趋势更明显;OAGB 组的叶酸水平升高幅度更大,白蛋白和血红蛋白下降趋势更明显。维生素 B12、D、铁和铁蛋白在两组之间没有差异,但组内存在差异。营养建议和采用的补充计划可最大程度地降低营养缺乏的风险,并在 OAGB 术后一年改善代谢生物标志物,与 SG 相比效果相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbfe/9268580/c4f41aa29d05/nutrients-14-02597-g001.jpg

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