Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, 411018, India.
CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, 110025, India.
Sci Rep. 2024 Jan 17;14(1):1504. doi: 10.1038/s41598-023-50317-8.
Numerous speculations have continually emerged, trying to explore the association between COVID-19 infection and a varied range of demographic and clinical factors. Frontline healthcare workers have been the primary group exposed to this infection, and there have been limited global research that examine this cohort. However, while there are a few large studies conducted on Indian healthcare professionals to investigate their potential risk and predisposing factors to COVID-19 infection, to our knowledge there are no studies evaluating the development of long COVID in this population. This cross-sectional study systematically utilized the demographic and clinical data of 3329 healthcare workers (HCW) from a tertiary hospital in India to gain significant insights into the associations between disease prevalence, severity of SARS-Cov-2 infection and long COVID. Most of the study population was found to be vaccinated (2,615, 78.5%), while 654 (19.65%) HCWs were found to be SARS-CoV-2 positive at least once. Of the infected HCWs, 75.1% (491) did not require hospitalization, whereas the rest were hospitalized for an average duration of 9 days. A total of 206 (6.19%) individuals were found to be suffering from long COVID. Persistent weakness/tiredness was the most experienced long-COVID symptom, while females (1.79, 1.25-2.57), individuals who consumed alcohol (1.85, 1.3-2.64) or had blood group B (1.9, 1.33-2.7) were at a significantly higher risk for developing long COVID.
人们不断提出各种推测,试图探讨新冠病毒感染与各种人口统计学和临床因素之间的关联。一线医护人员是接触这种感染的主要群体,但目前全球范围内对这一群体的研究有限。然而,尽管有一些针对印度医护人员的大型研究调查了他们感染新冠病毒的潜在风险和易患因素,但据我们所知,尚无研究评估该人群中长新冠的发展情况。本横断面研究系统地利用了印度一家三级医院的 3329 名医护人员的人口统计学和临床数据,深入了解了疾病流行率、新冠病毒感染严重程度与长新冠之间的关联。研究人群中大多数人已接种疫苗(2615 人,占 78.5%),而 654 人(19.65%)至少一次新冠病毒检测呈阳性。在感染的医护人员中,75.1%(491 人)无需住院,其余人平均住院 9 天。共有 206 人(6.19%)被诊断患有长新冠。持续乏力/疲劳是最常见的长新冠症状,而女性(1.79,1.25-2.57)、饮酒者(1.85,1.3-2.64)或血型为 B 型(1.9,1.33-2.7)的个体发生长新冠的风险显著更高。