Department of Nutrition, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang Province, People's Republic of China.
Department of Neurology, Epilepsy Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
J Health Popul Nutr. 2024 Jan 17;43(1):9. doi: 10.1186/s41043-024-00503-9.
BACKGROUND: In recent years, the impact of diet on Alzheimer's disease (AD) as a modifiable lifestyle has attracted widespread attention. We aimed to elucidate the current research status, frontiers, and research trends regarding the role of diet in AD over the past two decades through CiteSpace. METHODS: Studies related to AD and diet that were published from January 1, 2003, to June 30, 2023, were retrieved via the Web of Science Core Collection. We imported the study data into CiteSpace for visual analysis of countries, institutions, co-authors, and co-occurring keywords. RESULTS: A total of 922 relevant studies were included in our analysis, which found Nikolaos Scarmeas was the most prolific author (13 studies, 1.41%). The results also indicated that USA and Columbia University were the country and institution with the highest number of publications, with 209 (22.67%) and 23 (2.49%), respectively. The keywords that had a burst in the past four years were neuroinflammation, AD, tau, association, and beta. CONCLUSION: Talent exchange and regional cooperation are recommended in this study field. The results indicate that the effectiveness of various dietary patterns and mechanisms of dietary interventions using biomarkers and supplementation with refined nutrients will be the main research trends in the future.
背景:近年来,饮食对阿尔茨海默病(AD)的影响作为一种可改变的生活方式引起了广泛关注。我们旨在通过 CiteSpace 阐明过去 20 年来饮食在 AD 中的作用的当前研究现状、前沿和研究趋势。
方法:通过 Web of Science 核心合集检索 2003 年 1 月 1 日至 2023 年 6 月 30 日发表的与 AD 和饮食相关的研究。我们将研究数据导入 CiteSpace,用于分析国家、机构、合著者和共同出现的关键词的可视化。
结果:共纳入 922 项相关研究,其中 Nikolaos Scarmeas 是最具影响力的作者(13 项研究,1.41%)。结果还表明,美国和哥伦比亚大学是发表论文数量最多的国家和机构,分别为 209 项(22.67%)和 23 项(2.49%)。过去四年中爆发的关键词是神经炎症、AD、tau、关联和β。
结论:在该研究领域建议进行人才交流和区域合作。结果表明,各种饮食模式的有效性以及使用生物标志物和补充精制营养素进行饮食干预的机制将是未来的主要研究趋势。
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