Miki Reina, Kitajima Kazuhiro, Maeda Tetsuo, Watanabe Takahiro, Oki Noriyoshi
Department of Gynecology and Obstetrics, Chibune General Hospital, Osaka, Japan.
Department of Radiology, Hyogo Medical University, Nishinomiya, Japan.
Case Rep Oncol. 2024 Jan 17;17(1):107-112. doi: 10.1159/000534798. eCollection 2024 Jan-Dec.
Ovarian stromal tumors with minor sex cord elements are rare, and there are not specific imaging features to help in making the diagnosis.
We report a case of this tumor in an 81-year-old woman who was referred to our hospital for constipation and a pelvic mass. Magnetic resonance imaging demonstrated a well-circumscribed mass and isointensity compared to the skeletal muscle on T1-weighted imaging (T1WI) and low signal intensity mixed with high signal ranges on T2-weighted imaging. Dynamic gadolinium-enhanced fat-suppressed T1WI revealed mild and increased enhancement of the peripheral area in the early and delayed phases, respectively. On diffusion-weighted imaging (DWI), a heterogeneously high signal intensity corresponding to the peripheral enhanced area was observed, and the apparent diffusion coefficient values of the high-intensity areas on DWI were low. Malignancy could be suspected, so the mass was surgically removed. Pathological assessment revealed a fibrothecoma with minor sex cord elements.
The tumor's preoperative diagnosis is difficult, although the possibility of this rare tumor from atypical findings on DWI and/or dynamic contrast enhancement studies should be considered.
伴有少量性索成分的卵巢间质肿瘤较为罕见,且没有有助于诊断的特异性影像学特征。
我们报告一例81岁女性患有这种肿瘤,该患者因便秘和盆腔肿块转诊至我院。磁共振成像显示肿块边界清晰,在T1加权成像(T1WI)上与骨骼肌等信号,在T2加权成像上呈低信号强度并混合高信号区域。动态钆增强脂肪抑制T1WI显示,在早期和延迟期外周区域分别有轻度和增强增加。在扩散加权成像(DWI)上,观察到与外周增强区域相对应的不均匀高信号强度,DWI上高强度区域的表观扩散系数值较低。可能怀疑为恶性肿瘤,因此手术切除了肿块。病理评估显示为伴有少量性索成分的纤维瘤。
尽管应考虑这种罕见肿瘤在DWI和/或动态对比增强研究中出现非典型表现的可能性,但该肿瘤术前诊断困难。