Khalatyan A S, Yusef Yu N
Krasnov Research Institute of Eye Diseases, Moscow, Russia.
I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Vestn Oftalmol. 2023;139(6):158-165. doi: 10.17116/oftalma2023139061158.
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) and considered one of the leading causes of vision loss worldwide. The choroid supplies blood to the retina, photoreceptors and the retinal pigment epithelium, it is essential for metabolic exchange in the retina. Many experimental studies have reported that choroidal pathology in diabetic patients may play a role in the development of DR. Choroidal thickness (CT) can be used to assess the vascularization of the choroid. Choroidal vascularity index (CVI) is also used as a marker in assessment of choroidal vascularization. Many studies have been conducted to evaluate choroidal changes in various eye diseases. However, the data on CT in DM patients, especially in those with DR, are conflicting. Thus, the choroidal status in diabetic patients with or without DR remains controversial. In this systematic review we analyze a number of articles dedicated to the relationship between structural changes in the choroid in patients with diabetes mellitus and diabetic retinopathy of different stages, paying particular attention to choroidal thickness and certain other parameters that allow assessment of choroidal changes.
糖尿病性视网膜病变（DR）是糖尿病（DM）的一种微血管并发症，被认为是全球视力丧失的主要原因之一。脉络膜为视网膜、光感受器和视网膜色素上皮提供血液，对视网膜的代谢交换至关重要。许多实验研究报告称，糖尿病患者的脉络膜病变可能在DR的发生发展中起作用。脉络膜厚度（CT）可用于评估脉络膜的血管化程度。脉络膜血管指数（CVI）也被用作评估脉络膜血管化的一个指标。已经开展了许多研究来评估各种眼部疾病中的脉络膜变化。然而，关于糖尿病患者尤其是DR患者的CT数据存在矛盾。因此，糖尿病患者有无DR时的脉络膜状态仍存在争议。在本系统评价中，我们分析了多篇致力于探讨糖尿病患者脉络膜结构变化与不同阶段糖尿病性视网膜病变之间关系的文章，特别关注脉络膜厚度以及其他一些能够评估脉络膜变化的参数。
