De Guadalupe Quintana-Coronado María, Bravo Coral, Álvarez-Mon Melchor, Ortega Miguel A, De León-Luis Juan A
1 Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, Madrid, Spain.
2 Department of Obstetrics and Gynecology, University Hospital Gregorio Marañón, Madrid, Spain.
Front Pharmacol. 2024 Jan 4;14:1240032. doi: 10.3389/fphar.2023.1240032. eCollection 2023.
Obstetric diseases represent a highly complex medical challenge, especially regarding its clinical approach. The use of pharmacological agents during pregnancy is one of the main therapeutic alternatives in this group of patients; however, there is a general lack of knowledge about its use, efficacy, and possible adverse effects that may occur in routine clinical practice, even among medical professionals themselves. The high percentage of pregnant women who undergo drugs at some point during pregnancy, together with the developments that have occurred in recent years in the field of pharmacology, show the need for a detailed analysis that shows the existing current knowledge and helps in the clinical decision making. In this sense, the aim of this work is to conduct a review of the available scientific literature on the novelties in pharmacology for the main medical pathologies of pregnancy. Thus, the role of this field in analgesia, antibiotic therapy, digestive, respiratory, urological, psychiatric and neurological pathologies will be detailed, evaluating the indications, precautions and considerations that must be taken into account for its use.
产科疾病是一项极具复杂性的医学挑战，尤其是在临床治疗方面。孕期使用药物是这类患者主要的治疗选择之一；然而，即使是医学专业人员自身，对于其在常规临床实践中的使用、疗效以及可能出现的不良反应，普遍缺乏了解。在孕期某个阶段使用药物的孕妇比例很高，再加上近年来药理学领域的发展，表明需要进行详细分析，以展示现有的知识并有助于临床决策。从这个意义上讲，这项工作的目的是对妊娠主要医学病症药理学新进展的现有科学文献进行综述。因此，将详细阐述该领域在镇痛、抗生素治疗、消化、呼吸、泌尿、精神和神经病症中的作用，评估其使用时必须考虑的适应症、预防措施和注意事项。
