College of Nursing, Anhui University of Chinese Medicine, Hefei, China.
Medicine (Baltimore). 2024 Jan 19;103(3):e36601. doi: 10.1097/MD.0000000000036601.
The aim of this study was to identify the risk factors for posttraumatic stress disorder in patients with myocardial infarction.
Cohort, case-control, and cross-sectional studies on posttraumatic stress disorder (PTSD) in patients with myocardial infarction were searched from PubMed, Embase, Cochrane Library, Web of Science, China Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, and Technology Journal database. The Newcastle-Ottawa Quality Assessment Scale was used to score the quality of the included literature in the cohort and case-control studies, and the cross-sectional studies were scored using the American Agency for Health Care Quality and Research cross-sectional study quality evaluation criteria. The literature was screened independently by 2 researchers, and if there was no consensus, the inclusion was decided by a third party. The extraction content included first author, publication year, sample size, PTSD assessment tool, PTSD assessment time, PTSD incidence, influencing factors, and study type. Meta-analysis of data was performed using Stata17.0 software.
Ten studies were included, including 2 cohort studies, 7 cross-sectional studies, and 1 case-control study, with a total sample size of 2371 patients, including 26 influencing factors. The results of meta-analysis showed that the prevalence of PTSD in patients with myocardial infarction was 21.2%. Statistically significant influencing factors were gender (odd ratio [OR] = 3.124), neuroticism score (OR = 2.069), and age (OR = 0.913).
The prevalence of PTSD in patients with myocardial infarction in China is higher than that in other countries. Female and neurotic personality are risk factors for developing PTSD in patients with myocardial infarction, and old age is protective factor for developing PTSD in patients with myocardial infarction. Targeted measures should be taken to prevent and reduce the occurrence and development of PTSD in patients with myocardial infarction in the future.
本研究旨在确定心肌梗死后创伤后应激障碍的风险因素。
从 PubMed、Embase、Cochrane 图书馆、Web of Science、中国生物医学文献数据库、中国国家知识基础设施、万方数据知识服务平台和科技期刊数据库中搜索了有关心肌梗死后创伤后应激障碍（PTSD）的队列、病例对照和横断面研究。使用纽卡斯尔-渥太华质量评估量表对队列和病例对照研究中纳入文献的质量进行评分，使用美国医疗保健质量和研究机构横断面研究质量评估标准对横断面研究进行评分。由 2 名研究人员独立筛选文献，如果存在分歧，则由第三方决定纳入。提取内容包括第一作者、发表年份、样本量、PTSD 评估工具、PTSD 评估时间、PTSD 发生率、影响因素和研究类型。使用 Stata17.0 软件进行数据的荟萃分析。
共纳入 10 项研究，包括 2 项队列研究、7 项横断面研究和 1 项病例对照研究，共纳入 2371 例患者，包含 26 个影响因素。荟萃分析结果显示，心肌梗死后患者 PTSD 的发生率为 21.2%。有统计学意义的影响因素为性别（比值比[OR] = 3.124）、神经质评分（OR = 2.069）和年龄（OR = 0.913）。
中国心肌梗死后患者 PTSD 的发生率高于其他国家。女性和神经质人格是心肌梗死后患者发生 PTSD 的危险因素，年龄较大是心肌梗死后患者发生 PTSD 的保护因素。未来应采取针对性措施预防和减少心肌梗死后患者 PTSD 的发生和发展。
