Critical care resident, Universidad de La Sabana, Chía, Colombia.
Critical Medicine and Intensive Care, Intensive care department Fundación Clínica Shaio, Bogotá DC, Colombia.
BMC Pulm Med. 2024 Jan 19;24(1):41. doi: 10.1186/s12890-023-02753-5.
The SARS-CoV-2 pandemic resulted in shortages of supplies, which limited the use of extracorporeal membrane oxygenation (ECMO) support. As a contingency strategy, polypropylene (PP) oxygenation membranes were used. This study describes the clinical outcomes in patients on ECMO with PP compared to poly-methylpentene (PMP) oxygenation membranes.
Retrospective cohort of patients in ECMO support admitted between 2020 and 2021.
A total of 152 patients with ECMO support were included, 71.05% were men with an average age of 42 (SD 9.91) years. Veno-venous configuration was performed in 75.6% of cases. The PP oxygenation membranes required more changes 22 (63.1%), than the PMP Sorin® 24 (32,8%) and Euroset® 15 (31,9%) (p.0.022). The main indication for membrane change was low oxygen transfer for PP at 56.2%, Sorin® at 50%, and Euroset® at 14.8%. Renal replacement therapy was the most frequent complication with PP membrane in 22 patients (68.7%) Sorin® 25 patients (34.2%), and Euroset® 15 patients (31.9%) (p 0.001) without statistically significant differences in mortality.
PP oxygenation membranes was a useful and feasible strategy. It allowed a greater disponibility of ECMO support for critically ill in a situation of great adversity during the SARS-CoV-2 pandemic.
SARS-CoV-2 大流行导致供应短缺，这限制了体外膜肺氧合（ECMO）的使用。作为应急策略，使用了聚丙烯（PP）氧合膜。本研究描述了与聚甲基戊烯（PMP）氧合膜相比，在 ECMO 上使用 PP 的患者的临床结局。
回顾性纳入 2020 年至 2021 年期间接受 ECMO 支持的患者队列。
共纳入 152 名接受 ECMO 支持的患者，71.05%为男性，平均年龄为 42（SD 9.91）岁。75.6%的患者采用静脉-静脉配置。PP 氧合膜需要更多的更换 22 次（63.1%），而 PMP Sorin® 24 次（32.8%）和 Euroset® 15 次（31.9%）（p.0.022）。更换膜的主要指征是 PP 膜的氧传递率低，为 56.2%，Sorin®为 50%，Euroset®为 14.8%。肾替代治疗是最常见的并发症，PP 膜 22 例（68.7%），Sorin®25 例（34.2%），Euroset®15 例（31.9%）（p 0.001），死亡率无统计学差异。
PP 氧合膜是一种有用且可行的策略。在 SARS-CoV-2 大流行期间，在极端困难的情况下，它为重症患者提供了更多的 ECMO 支持。
