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保留雷济厄斯间隙的机器人辅助根治性前列腺切除术能否确保所有年龄段患者都实现最佳尿控恢复?

Does Retzius-Sparing robot-assisted radical prostatectomy guarantee optimal urinary continence recovery across all ages?

作者信息

Dell'Oglio Paolo, Tappero Stefano, Maltzman Ofir, Olivero Alberto, Secco Silvia, Di Trapani Dario, Bocciardi Aldo Massimo, Galfano Antonio

机构信息

Department of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Department of Urology, Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

出版信息

Prostate Cancer Prostatic Dis. 2025 Mar;28(1):226-228. doi: 10.1038/s41391-023-00784-x. Epub 2024 Jan 20.

Abstract

The association between age at surgery and urinary continence (UC) recovery after Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) is not well established. We addressed this knowledge gap, relying on a large series of 1,417 patients treated with RS-RARP at a high-volume centre between 2010 and 2021. Multivariable logistic models, as well as LOESS plot functions were performed. The probability of immediate, as well as 12-month UC-recovery progressively declined with increasing age at surgery, and per 5-years age at surgery increase reached the independent predictor status for both immediate and 12-month UC-recovery. These findings may significantly improve the quality of patient counseling regarding RS-RARP.

摘要

保留耻骨后间隙机器人辅助根治性前列腺切除术(RS-RARP)后手术年龄与尿失禁(UC)恢复之间的关联尚未明确。我们依据2010年至2021年间在一家高容量中心接受RS-RARP治疗的1417例患者的大量病例,填补了这一知识空白。进行了多变量逻辑模型以及局部加权回归散点平滑(LOESS)绘图函数分析。即刻及12个月UC恢复的概率随着手术年龄的增加而逐渐下降,手术年龄每增加5岁,即刻及12个月UC恢复均达到独立预测指标的地位。这些发现可能会显著提高关于RS-RARP患者咨询的质量。

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