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Haptoglobin Gene Polymorphism Is Associated With Lower Postoperative Cardiovascular Risk in Carotid Stenosis Patients.

作者信息

Mohsen Yazan, Shami Annelie, Edsfeldt Andreas, Sun Jiangming, Gonçalves Isabel

机构信息

Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

Department of Cardiology, Electrophysiology and Rhythmology, Hospital Porz am Rhein, Cologne, Germany.

出版信息

J Stroke. 2024 Jan;26(1):125-128. doi: 10.5853/jos.2023.03349. Epub 2024 Jan 22.

DOI:10.5853/jos.2023.03349
PMID:38246719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10850447/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13be/10850447/4407d96ed55b/jos-2023-03349f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13be/10850447/4407d96ed55b/jos-2023-03349f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13be/10850447/4407d96ed55b/jos-2023-03349f1.jpg

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Haptoglobin Gene Polymorphism Is Associated With Lower Postoperative Cardiovascular Risk in Carotid Stenosis Patients.触珠蛋白基因多态性与颈动脉狭窄患者较低的术后心血管风险相关。
J Stroke. 2024 Jan;26(1):125-128. doi: 10.5853/jos.2023.03349. Epub 2024 Jan 22.
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The haptoglobin 2-2 genotype is associated with carotid atherosclerosis in 64-year old women with established diabetes.携带血红蛋白 2-2 基因型的 64 岁女性,患有已确诊的糖尿病,其颈动脉粥样硬化的风险增加。
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Gene polymorphism of apolipoprotein AI, the major protein of high density lipoprotein in predicting stroke risk among white and black subjects.
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本文引用的文献

1
Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes.触珠蛋白基因型与 1 型糖尿病患者卒中风险无关。
Diabetes. 2022 Dec 1;71(12):2728-2738. doi: 10.2337/db22-0327.
2
Haptoglobin as a Biomarker.触珠蛋白作为一种生物标志物。
Biochem Mosc Suppl B Biomed Chem. 2021;15(3):184-198. doi: 10.1134/S1990750821030069. Epub 2021 Aug 16.
3
Haptoglobin genotype 2-2 associated with atherosclerosis in patients with ischemic stroke.携带 2-2 型触珠蛋白基因型与缺血性脑卒中患者的动脉粥样硬化相关。
Gene. 2020 Aug 20;752:144786. doi: 10.1016/j.gene.2020.144786. Epub 2020 May 18.
4
Haptoglobin Phenotype Modifies the Influence of Intensive Glycemic Control on Cardiovascular Outcomes.结合珠蛋白表型改变强化血糖控制对心血管结局的影响。
J Am Coll Cardiol. 2020 Feb 11;75(5):512-521. doi: 10.1016/j.jacc.2019.11.051.
5
Recurring exon deletions in the HP (haptoglobin) gene contribute to lower blood cholesterol levels.触珠蛋白(HP)基因中反复出现的外显子缺失会导致血液胆固醇水平降低。
Nat Genet. 2016 Apr;48(4):359-66. doi: 10.1038/ng.3510. Epub 2016 Feb 22.
6
The Risk of Coronary Heart Disease Associated With Glycosylated Hemoglobin of 6.5% or Greater Is Pronounced in the Haptoglobin 2-2 Genotype.在触珠蛋白2-2基因型中,糖化血红蛋白水平为6.5%及以上与冠心病风险之间的关联十分显著。
J Am Coll Cardiol. 2015 Oct 20;66(16):1791-1799. doi: 10.1016/j.jacc.2015.07.076.
7
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events.触珠蛋白 2 等位基因与不稳定颈动脉斑块和主要心血管事件相关。
Atherosclerosis. 2013 Oct;230(2):228-34. doi: 10.1016/j.atherosclerosis.2013.07.008. Epub 2013 Jul 25.
8
Inheritance of haptoglobin subtypes.触珠蛋白亚型的遗传。
Am J Hum Genet. 1962 Mar;14(1):14-21.
9
Structure-function analysis of the antioxidant properties of haptoglobin.触珠蛋白抗氧化特性的结构-功能分析
Blood. 2001 Dec 15;98(13):3693-8. doi: 10.1182/blood.v98.13.3693.