Panter K E, Ralphs M H, Smart R A, Duelke B
Vet Hum Toxicol. 1987 Feb;29(1):45-8.
Approximately 250 sheep were poisoned and died from ingesting death camas (Zygadenus paniculatus) within a 2-day period on a foothill range in southeastern Idaho. Sixty to 70% of the poisoned sheep were 80-90 lb lambs and the rest were mature ewes. Poisonings were confirmed by field investigation, microhistological analysis of plant fragments from rumen contents of dead sheep, clinical signs, gross and microscopic analysis of tissues, and by experimentally feeding death camas collected on the poisoning site to 3 ewes at the Poisonous Plant Research Laboratory at Logan, UT. Clinical signs and gross and microscopic analysis of tissues were similar in ewes from the field investigation to those in ewes experimentally fed death camas. Ataxia, muscular weakness, trembling, incoordination, discharge of frothy saliva from the mouth and nose, vomition, dyspnea, collapse and death were the most common clinical signs. Gross changes included severe pulmonary congestion and subcutaneous hemorrhage. Microscopic lesions were those of severe pulmonary congestion.
在爱达荷州东南部的一个山麓牧场，大约250只绵羊在两天内因误食棋盘花（Zygadenus paniculatus）而中毒死亡。中毒绵羊中有60%至70%是体重80至90磅的羔羊，其余为成年母羊。通过实地调查、对死羊瘤胃内容物中的植物碎片进行显微组织学分析、临床症状、组织的大体和显微镜分析，以及在犹他州洛根的有毒植物研究实验室将在中毒现场采集的棋盘花喂给3只母羊进行实验，证实了中毒情况。实地调查中母羊的临床症状以及组织的大体和显微镜分析结果与实验喂食棋盘花的母羊相似。共济失调、肌肉无力、颤抖、不协调、口鼻流出泡沫状唾液、呕吐、呼吸困难、虚脱和死亡是最常见的临床症状。大体变化包括严重的肺充血和皮下出血。显微镜下病变为严重的肺充血。
