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评估激光疗法和自体富血小板血浆(PRP)治疗慢性伤口的疗效。

Assessing the Efficacy of Laser Therapy and Autologous Platelet-Rich Plasma (PRP) Treatment for Chronic Wounds.

作者信息

Mircea Sandor, Laura Maghiar, Sebastian Horgos Maur, Lucian Borza Ioan, Maria Farcas Dorina, Daniel Ciurescu, Dragos Cheregi Cornel, Loredana Hurjui Liliana, Liliana Sachelarie, Bianca Maghiar Paula

机构信息

Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.

Preclinical Sciences Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.

出版信息

J Pers Med. 2024 Jan 11;14(1):85. doi: 10.3390/jpm14010085.

DOI:10.3390/jpm14010085
PMID:38248786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10817496/
Abstract

(1) Background: The management of persistent wounds is a topic of significant concern, particularly when they become chronic. Clinicians are focused on reducing the healing duration of chronic wounds and employing the most efficient treatments. Successful wound management requires an understanding of standard healing processes, the elements that can impede healing progress, and strategies to manage these impediments. (2) Methods: We participated in a study involving a cohort of 115 patients. Data were collected through subjective assessments via questionnaires, examining the comparative effects of laser therapy and platelet-rich plasma (PRP) on patients' conditions and monitored the progression of chronic wounds. For the study, we utilized a branded laser equipped with a 12-watt probe to stimulate chronic wounds in 65 patients, while the PRP procedure was administered to 50 patients. (3) Results: We observed a greater improvement in local symptoms among the patients who received laser therapy compared to those in the PRP group. (4) Conclusions: We consider both therapies to be of significant importance due to their positive and beneficial effects, particularly on the symptomatology and progression of chronic wounds. Nevertheless, superior results were documented in patients who underwent laser therapy.

摘要

(1) 背景:持续性伤口的处理是一个备受关注的话题,尤其是当它们发展为慢性伤口时。临床医生致力于缩短慢性伤口的愈合时间并采用最有效的治疗方法。成功的伤口处理需要了解标准的愈合过程、可能阻碍愈合进程的因素以及应对这些阻碍的策略。(2) 方法:我们参与了一项涉及115名患者的队列研究。通过问卷调查进行主观评估收集数据,考察激光治疗和富血小板血浆(PRP)对患者病情的比较效果,并监测慢性伤口的进展情况。在该研究中,我们使用一台配备12瓦探头的品牌激光设备对65名患者的慢性伤口进行刺激,同时对50名患者实施PRP治疗。(3) 结果:我们观察到,与PRP组患者相比,接受激光治疗的患者局部症状改善更为明显。(4) 结论:由于这两种疗法都具有积极有益的效果,特别是对慢性伤口的症状和进展,我们认为它们都非常重要。然而,接受激光治疗的患者取得了更优的结果。

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本文引用的文献

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Efficacy of Intralesional Platelet-Rich Plasma in Diabetic Foot Ulcer.富血小板血浆局部注射治疗糖尿病足溃疡的疗效。
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Topical Wound Medications.局部伤口用药
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[Clinical application of platelet-rich fibrin in chronic wounds combined with subcutaneous stalking sinus].富血小板纤维蛋白在慢性伤口合并皮下潜行性窦道中的临床应用
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A contemporary view of platelet-rich plasma therapies: moving toward refined clinical protocols and precise indications.富血小板血浆疗法的当代观点:迈向精细化临床方案与精准适应症
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