Fanous Rafik
Family Medicine, Stourport Medical Centre, Stourport-on-Severn, GBR.
Cureus. 2023 Dec 21;15(12):e50878. doi: 10.7759/cureus.50878. eCollection 2023 Dec.
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer that can present with various clinical manifestations. An 80-year-old male, known to have chronic lymphocytic leukaemia presented with a lesion on his left thumb, initially thought to be a pyogenic granuloma. The lesion was cauterized with silver nitrate but remained persistent. A curettage biopsy was performed, and a histopathological examination revealed MCC. The patient was subsequently referred to dermatology and plastic surgery for further management. The lesion was excised; a full-thickness skin graft was used to close the defect. This case highlights the importance of considering MCC in the differential diagnosis of skin lesions, even if they present with a benign appearance.
默克尔细胞癌(MCC)是一种罕见且侵袭性强的皮肤癌,可表现出多种临床表现。一名80岁男性,已知患有慢性淋巴细胞白血病,其左手拇指出现一处皮损,最初被认为是化脓性肉芽肿。该皮损用硝酸银烧灼,但仍持续存在。进行了刮除活检,组织病理学检查显示为MCC。该患者随后被转诊至皮肤科和整形外科进行进一步治疗。切除了皮损;采用全厚皮片移植来闭合缺损。该病例强调了在皮肤病变的鉴别诊断中考虑MCC的重要性,即使它们表现出良性外观。