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计算精神病学的现状、挑战与未来前景:一篇叙述性综述。

Current status, challenges and future prospects in computational psychiatry: a narrative review.

作者信息

Vasilchenko Kirill F, Chumakov Egor M

机构信息

The Human artificial control Keren (HacK) lab, Azrieli Faculty of Medicine, Bar-Ilan University.

Saint Petersburg State University.

出版信息

Consort Psychiatr. 2023 Sep 29;4(3):33-42. doi: 10.17816/CP11244.

Abstract

BACKGROUND

Computational psychiatry is an area of scientific knowledge which lies at the intersection of neuroscience, psychiatry, and computer science. It employs mathematical models and computational simulations to shed light on the complexities inherent to mental disorders.

AIM

The aim of this narrative review is to offer insight into the current landscape of computational psychiatry, to discuss its significant challenges, as well as the potential opportunities for the fields growth.

METHODS

The authors have carried out a narrative review of the scientific literature published on the topic of computational psychiatry. The literature search was performed in the PubMed, eLibrary, PsycINFO, and Google Scholar databases. A descriptive analysis was used to summarize the published information on the theoretical and practical aspects of computational psychiatry.

RESULTS

The article relates the development of the scientific approach in computational psychiatry since the mid-1980s. The data on the practical application of computational psychiatry in modeling psychiatric disorders and explaining the mechanisms of how psychopathological symptomatology develops (in schizophrenia, attention-deficit/hyperactivity disorder, autism spectrum disorder, anxiety disorders, obsessive-compulsive disorder, substance use disorders) are summarized. Challenges, limitations, and the prospects of computational psychiatry are discussed.

CONCLUSION

The capacity of current computational technologies in psychiatry has reached a stage where its integration into psychiatric practice is not just feasible but urgently needed. The hurdles that now need to be addressed are no longer rooted in technological advancement, but in ethics, education, and understanding.

摘要

背景

计算精神病学是一个处于神经科学、精神病学和计算机科学交叉领域的科学知识范畴。它运用数学模型和计算模拟来揭示精神障碍所固有的复杂性。

目的

本叙述性综述的目的是深入洞察计算精神病学的当前状况,讨论其重大挑战以及该领域发展的潜在机遇。

方法

作者对关于计算精神病学主题发表的科学文献进行了叙述性综述。文献检索在PubMed、电子图书馆、PsycINFO和谷歌学术数据库中进行。采用描述性分析来总结已发表的关于计算精神病学理论和实践方面的信息。

结果

本文阐述了自20世纪80年代中期以来计算精神病学中科学方法的发展。总结了计算精神病学在对精神障碍进行建模以及解释精神病理症状学(在精神分裂症、注意力缺陷多动障碍、自闭症谱系障碍、焦虑症、强迫症、物质使用障碍中)如何发展的机制方面的实际应用数据。讨论了计算精神病学的挑战、局限性和前景。

结论

当前计算技术在精神病学中的能力已达到一个阶段,即其融入精神病学实践不仅可行,而且迫切需要。现在需要解决的障碍不再源于技术进步,而是源于伦理、教育和理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e77b/10795945/33cb2aaece44/2712-7672-2023-4-3-11244-g001.jpg

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