Scarpellini Raffaele, Giunti Massimo, Bulgarelli Cecilia, Mondo Elisabetta, Esposito Erika, Assirelli Giammarco, Piva Silvia
Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Front Vet Sci. 2024 Jan 5;10:1261925. doi: 10.3389/fvets.2023.1261925. eCollection 2023.
A 14-year-old female domestic short-haired cat with a diagnosed diabetes mellitus and acromegaly was presented for lethargy and dysorexia. On clinical presentation, the patient showed hyperglycemia, hyperthermia, dull mentation, and dehydration. With the suspicion of an inflammatory or infectious complication of diabetes, she was hospitalized with constant rate infusion of insulin, and empirical ampicillin sulbactam was started. Blood culture revealed positivity for and the septic picture was confirmed by blood analysis, with leukocytosis, neutrophilia, and an increased serum amyloid A concentration. The isolated strain showed susceptibility to every antimicrobial tested. During the second day of hospitalization, the onset of hypoglycemia and hypotension was treated with norepinephrine and glucose in fluid therapy. The cat recovered well and was discharged with insulin and amoxicillin-clavulanate. This is the first case of septicemia associated with in a cat, suspected of developing the infection after contact with natural reservoirs such as rodents or birds. This route of transmission should be highlighted especially in relation to the zoonotic potential of the bacteria.
一只14岁的雌性家养短毛猫,已确诊患有糖尿病和肢端肥大症,因嗜睡和食欲不振前来就诊。临床表现为高血糖、体温过高、精神萎靡和脱水。由于怀疑是糖尿病的炎症或感染并发症,该猫住院并持续静脉输注胰岛素,同时开始经验性使用氨苄西林舒巴坦。血培养显示[具体细菌名称]呈阳性,血液分析证实了败血症的情况,表现为白细胞增多、中性粒细胞增多以及血清淀粉样蛋白A浓度升高。分离出的[具体细菌名称]菌株对所测试的每种抗菌药物均敏感。住院第二天,通过液体疗法使用去甲肾上腺素和葡萄糖治疗低血糖和低血压的发作。这只猫恢复良好,出院时携带胰岛素和阿莫西林克拉维酸。这是首例猫感染[具体细菌名称]导致败血症的病例,怀疑是在与啮齿动物或鸟类等自然宿主接触后感染。尤其考虑到该细菌的人畜共患病潜力,应强调这种传播途径。