Anders O, Preussner S, Konrad H
Z Gesamte Inn Med. 1986 Nov 1;41(21):592-5.
The clinical use of the transfusion of thrombocytes, its indication and problems in the long-term substitution of thrombocytes are explained. Out of the side effects the alloimmunisation against antigens of the HLA-system in the long-term substitution is of greatest importance. A substitution of thrombocytes is indicated in the disturbances of formation. The substitution shall be performed prophylactically in the acute leukaemia and aplasing therapy. When an increased destruction of thrombocytes is existing, other therapy principles are important. Recommendations are given for the prophylactic substitution of thrombocytes. The analysis of the transfusion of 320 concentrates of thrombocytes is reported.
本文解释了血小板输注的临床应用、其适应症以及长期血小板替代治疗中的问题。在副作用中，长期替代治疗中针对HLA系统抗原的同种免疫最为重要。血小板替代治疗适用于造血功能障碍。在急性白血病和再生障碍性贫血的治疗中应进行预防性替代治疗。当存在血小板破坏增加的情况时，其他治疗原则很重要。文中给出了血小板预防性替代治疗的建议。报告了对320份血小板浓缩液输注情况的分析。
