University Institute of Bioengineering, Chandigarh University, Gharuan, Mohali, Punjab, 140413, India.
University Institute of Biotechnology, Chandigarh University, Gharuan, Mohali, Punjab, 140413, India.
Naunyn Schmiedebergs Arch Pharmacol. 2024 Jul;397(7):4483-4497. doi: 10.1007/s00210-024-02964-5. Epub 2024 Jan 22.
Rubus ellipticus Smith. (Family Rosaceae), often known as the yellow Himalayan raspberry (Yellow Hissar), is one of the most widely used edible fruits in Indian folk medicinal systems. The current review aims to identify the gap between research and existing applications of this fruit to help scientists explore the current trends and opportunities for future development. Fruits of R. ellipticus are the source of several classes of compounds. Fruits of R. ellipticus are also rich in nutrients such as carbohydrates, vitamins, and minerals. It has been shown to have significant medical value in a variety of studies, including as an anti-diabetic, nephroprotective, anti-inflammatory, analgesic, antipyretic, antitumor, wound healing, antifertility, oviposition deterrent, antibacterial, and antioxidant. Fruits of R. ellipticus have been the subject of several in vitro and in vivo investigations, all of which have corroborated their wide range of biological activities and demonstrated their potential for the identification of new therapeutic candidates and the development of innovative herbal food supplements. Additional mechanism-based pharmacological evaluation and clinical research should provide an adequate scientific basis for the traditional usage of R. ellipticus fruits, which is currently not sufficiently supported by the available research on its active components and molecular mechanisms.
山莓（Family Rosaceae），通常被称为黄色喜马拉雅覆盆子（Yellow Hissar），是印度民间药用系统中最广泛使用的食用水果之一。本综述旨在确定该水果的研究现状与现有应用之间的差距，以帮助科学家探索当前的趋势和未来发展的机会。山莓的果实是几类化合物的来源。山莓的果实还富含碳水化合物、维生素和矿物质等营养物质。多项研究表明，它具有重要的药用价值，包括抗糖尿病、肾保护、抗炎、镇痛、解热、抗肿瘤、伤口愈合、抗生育、产卵抑制、抗菌和抗氧化作用。山莓的果实已经成为多项体外和体内研究的主题，所有这些研究都证实了其广泛的生物活性，并展示了它们在鉴定新的治疗候选物和开发创新的草药食品补充剂方面的潜力。基于机制的药理学评价和临床研究的增加，应该为山莓果实的传统用途提供充分的科学依据，而目前其活性成分和分子机制的研究还不足以支持其传统用途。
