Department of Legal Medicine, Dokkyo Medical University. 880, Kitakobayashi, Mibu-cho, Shimotsuga-gun, Tochigi 321-0293, Japan; Tokyo Medical Examiner's Office, 4-21-18, Otsuka, Bunkyo-ku, Tokyo 112-0012, Japan.
Tokyo Medical Examiner's Office, 4-21-18, Otsuka, Bunkyo-ku, Tokyo 112-0012, Japan.
Cardiovasc Pathol. 2024 Mar-Apr;69:107607. doi: 10.1016/j.carpath.2024.107607. Epub 2024 Jan 20.
Cystic tumor of the atrioventricular node (CTAVN) is the most common primary cardiac tumor cause of sudden death but is rarely found during forensic autopsy. We present five autopsy cases of sudden death from undiagnosed CTAVN. The tumors varied in their histological appearance, which may be related to their variation in clinical presentation. Some of the cases had been diagnosed with epilepsy before death; it seems that syncopal attacks caused by CTAVN may be misdiagnosed as epilepsy. When performing forensic autopsy, CTAVN should be considered in the differential diagnosis of sudden death. Careful examination of the cardiac conduction system is important in every sudden death case regardless of age.
房室结囊性肿瘤（CTAVN）是最常见的原发性心内肿瘤，也是导致心源性猝死的主要原因，但在法医尸检中很少发现。我们报道了 5 例因未经诊断的 CTAVN 而猝死的尸检病例。肿瘤的组织学表现存在差异，这可能与其临床表现的差异有关。一些病例在死亡前被诊断为癫痫；看来由 CTAVN 引起的晕厥发作可能被误诊为癫痫。在进行法医尸检时，对于猝死的鉴别诊断应考虑 CTAVN。无论年龄大小，在每个猝死病例中仔细检查心脏传导系统都很重要。
