原发性和复发性骨内腺样囊性癌——两例分析及文献复习。

Primary and Recurrent Intraosseous Adenoid Cystic Carcinoma-Analysis of Two Cases and Literature Review.

机构信息

Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Department of Stomatology, Zhejiang University School of Medicine, Hangzhou 310058, China.

出版信息

Medicina (Kaunas). 2024 Jan 5;60(1):100. doi: 10.3390/medicina60010100.

DOI:10.3390/medicina60010100

PMID:38256362

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10820229/

Abstract

Adenoid cystic carcinoma (ACC) is a rare malignant tumor that mostly occurs in minor glands, especially in the palate. Intraosseous adenoid cystic carcinoma (IACC) is rarer. There is no clear conclusion on the clinical, radiologic and pathological characteristics of IACC because of few reported IACC cases, leading to insufficient understanding of IACC. We reviewed 52 previous reports of primary IACC (PIACC) and analyzed the clinical features of those patients involved, attempting to provide a better understanding of PIACC. Moreover, we present a case of primary PIACC and a case of recurrent IACC (RIACC). The two patients showed similarities in clinical and pathological results, along with slight differences in radiological and immunohistochemical results. The patient of case 1 seemed to display a worse prognosis, which can only be proved after long term follow-up.

摘要

腺样囊性癌（ACC）是一种罕见的恶性肿瘤，主要发生在小腺体，特别是在腭部。骨内腺样囊性癌（IACC）则更为罕见。由于报道的 IACC 病例较少，对其临床、放射学和病理学特征尚无明确结论，导致对 IACC 的认识不足。我们回顾了 52 例原发性 IACC（PIACC）的既往报告，并分析了涉及的患者的临床特征，试图更好地了解 PIACC。此外，我们还报告了 1 例原发性 PIACC 和 1 例复发性 IACC（RIACC）病例。这两例患者的临床和病理结果相似，而放射学和免疫组织化学结果略有不同。病例 1 的患者似乎预后较差，但只能通过长期随访来证明。