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可持续藻类衍生纳米乳液的配方与表征:一种减少对合成表面活性剂依赖的绿色方法

Formulation and Characterization of Sustainable Algal-Derived Nanoemulgels: A Green Approach to Minimize the Dependency on Synthetic Surfactants.

作者信息

Tello Patricia, Santos Jenifer, Calero Nuria, Trujillo-Cayado Luis A

机构信息

Departamento de Ingeniería Química, Escuela Politécnica Superior, Universidad de Sevilla, c/Virgen de África, 7, 41011 Sevilla, Spain.

Departamento de Ciencias de la Salud y Biomédicas, Facultad de Ciencias de la Salud, Universidad Loyola Andalucía, Avda. de las Universidades s/n, 41704 Dos Hermanas, Sevilla, Spain.

出版信息

Polymers (Basel). 2024 Jan 9;16(2):194. doi: 10.3390/polym16020194.

DOI:10.3390/polym16020194
PMID:38256993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10819741/
Abstract

Phycocyanin (PC), a natural protein that is very interesting from the medical point of view due to its potent antioxidant and anti-inflammatory properties, is obtained from algae. This compound is gaining positions for applications in the food industry. The main objective of this work was to obtain nanoemulgels formulated with PC and k-carrageenan (a polymer that is obtained from algae as well). An optimization of the processing parameters (homogenization pressure and number of cycles) and the ratio of PC and a well-known synthetic surfactant (Tween 80) was developed using response surface methodology. The results of this optimization were 25,000 psi, seven cycles, and a 1:1 ratio of PC/Tween80. However, the necessity for the incorporation of a polymer that plays a thickener role was observed. Hence, k-carrageenan (k-C) was used to retard the creaming process that these nanoemulsions suffered. The incorporation of this biopolymer provoked the creation of a network that showed gel-type behavior and flow indexes very close to zero. Thanks to the combined use of these two sustainable and algae-obtained compounds, stable nanoemulgels were obtained. This work has proved that the combined use of PC and k-C has emerged as a sustainable alternative to stabilize dispersed systems for the food industry.

摘要

藻蓝蛋白(PC)是一种天然蛋白质,因其具有强大的抗氧化和抗炎特性而从医学角度来看非常有趣,它是从藻类中提取的。这种化合物在食品工业中的应用正在逐渐增加。这项工作的主要目标是获得用PC和κ-卡拉胶(一种同样从藻类中获得的聚合物)配制的纳米乳凝胶。使用响应面法对加工参数(均质压力和循环次数)以及PC与一种知名合成表面活性剂(吐温80)的比例进行了优化。该优化的结果是25000 psi、七个循环以及PC/吐温80的比例为1:1。然而,观察到需要加入一种起增稠剂作用的聚合物。因此,使用κ-卡拉胶(κ-C)来延缓这些纳米乳液所经历的乳析过程。这种生物聚合物的加入促使形成了一个表现出凝胶型行为且流动指数非常接近零的网络。由于这两种可持续且从藻类中获得的化合物的联合使用,获得了稳定的纳米乳凝胶。这项工作证明,PC和κ-C的联合使用已成为一种可持续的替代方案,用于稳定食品工业中的分散体系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/505fba32c219/polymers-16-00194-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/6707447d1efa/polymers-16-00194-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/8828dc49a24b/polymers-16-00194-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/ce2b742c9e69/polymers-16-00194-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/807c1484af72/polymers-16-00194-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/952f02ffa232/polymers-16-00194-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/0e6c5447608b/polymers-16-00194-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/2244b8e2004f/polymers-16-00194-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/505fba32c219/polymers-16-00194-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/6707447d1efa/polymers-16-00194-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/8828dc49a24b/polymers-16-00194-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/ce2b742c9e69/polymers-16-00194-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/807c1484af72/polymers-16-00194-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/952f02ffa232/polymers-16-00194-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/0e6c5447608b/polymers-16-00194-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/2244b8e2004f/polymers-16-00194-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/10819741/505fba32c219/polymers-16-00194-g008.jpg

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Pharmaceutics. 2023 Aug 1;15(8):2067. doi: 10.3390/pharmaceutics15082067.
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Pickering emulsions stabilized with a spirulina protein-chitosan complex for astaxanthin delivery.
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